Let (g, g) be a pair of complex finite-dimensional simple Lie algebras whose Dynkin diagrams are related by (un)folding, with g being of simply-laced type. We construct a collection of ring isomorphisms between the quantum Grothendieck rings of monoidal categories Cg and Cg of finite-dimensional representations over the quantum loop algebras of g and g respectively. As a consequence, we solve longstanding problems : the positivity of the analogs of Kazhdan-Lusztig polynomials and the positivity of the structure constants of the quantum Grothendieck rings for any non-simply-laced g. In addition, comparing our isomorphisms with the categorical relations arising from the generalized quantum affine Schur-Weyl dualities, we prove the analog of Kazhdan-Lusztig conjecture (formulated in [17]) for simple modules in remarkable monoidal subcategories of Cg for any non-simply-laced g, and for any simple finite-dimensional modules in Cg for g of type Bn. In the course of the proof we obtain and combine several new ingredients. In particular we establish a quantum analog of T -systems, and also we generalize the isomorphisms of [24,26] to all g in a unified way, that is isomorphisms between subalgebras of the quantum group of g and subalgebras of the quantum Grothendieck ring of Cg.