Could the oral cavity be a target organ in SARS-CoV-2 infection?

Kumar, Satish

doi:10.1038/s41432-021-0174-2

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…Dysgeusia can manifest in the majority of patients within 5 days of receiving a COVID-19 diagnosis, and it typically lasts for 2 weeks, or up to 4 weeks in more severe cases ( Amorim dos Santos et al, 2021a ). It was discovered that the degree of dysgeusia was strongly correlated with the severity of COVID-19, and that severe dysgeusia served as a warning sign ( Amorim dos Santos et al, 2021a ; Kumar, 2021 ). It is interesting that among COVID-19 patients, there was no statistically significant difference in the alterations of the tastes of sour, sweet, salty, or spicy ( Biadsee et al, 2020 ).…”

Section: Oral Manifestations Of Covid-19mentioning

confidence: 99%

The oral manifestations and related mechanisms of COVID-19 caused by SARS-CoV-2 infection

Lin

Gao

Wang

et al. 2023

Front. Cell. Neurosci.

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Coronavirus disease 2019 (COVID-19) was reported to be associated with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, and patients present mostly with respiratory symptoms. There have been an increasing number of reports on oral manifestations, and some of these signs are informative in terms of identifying SARS-CoV-2 infection. The goal of present study was to review and synthesize the clinical characteristics and underlying mechanisms of COVID-19 oral manifestations, as well as to evaluate the factors influencing SARS-CoV-2 infectivity, in order to conduct further in-depth investigations and help clinicians diagnose COVID-19 patients exhibiting oral symptoms.

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Section: Oral Manifestations Of Covid-19mentioning

confidence: 99%

The oral manifestations and related mechanisms of COVID-19 caused by SARS-CoV-2 infection

Lin

Gao

Wang

et al. 2023

Front. Cell. Neurosci.

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“…In a comment published, Kumar S. highlighted that oral manifestations are likely to take place in advance together with loss of taste and smell in some patients with SARS-CoV-2 infection and may be a valuable early indication for COVID-19, so rapid follow-up testing is recommended [63].…”

Section: Pbmt and Antimicrobial Photodynamic Therapy In The Covid Eramentioning

confidence: 99%

Light as a Cure in COVID-19: A Challenge for Medicine

Ailioaie

Ailioaie²,

Litscher³

2022

Photonics

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Light and lasers, as high-tech devices whose medical potential has yet to be fully discovered, have made important contributions to medicine, even in the current pandemic. The main aim of this review was to investigate how light was applied as a therapeutic tool during a crisis triggered by COVID-19. Another goal was to encourage scientists and industry to quickly design new at-home photobiomodulation therapy (PBMT) and/or antimicrobial photodynamic therapy (aPDT) easy to use systems to end this pandemic, especially for those who believe in high-tech but would never get vaccinated. This review revealed that PBMT has been successfully applied as adjunct therapy, in combination with conventional medical treatment, and as a pioneering action in SARS-CoV-2 infection, demonstrating significant improvements in airway inflammation and general clinical condition of patients, a faster recovery, avoiding intensive care unit (ICU) hospitalization, mechanical ventilation, mortality, and overcoming long-term sequelae. Application in only a limited number of cases strongly suggests the need for future randomized, placebo-controlled clinical trials to objectively determine the action and effects of PBMT in COVID-19. Implementation of unparalleled theragnostics methods and light-based techniques for disinfection of spaces, air, skin, mucosae, and textures to decrease the load of SARS-CoV-2 virus would save lives, time, and money. In this ongoing and challenging search for the seemingly intangible end of this pandemic, a non-invasive, easily accessible, safe, and side-effect-free adjuvant method appears to be PBMT, alone or in synergistic combination with aPDT, which has been shown to work in COVID-19 and opens unprecedented potential for use as home self-treatment to end the pandemic.

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Could the oral cavity be a target organ in SARS-CoV-2 infection?

Cited by 2 publications

References 16 publications

The oral manifestations and related mechanisms of COVID-19 caused by SARS-CoV-2 infection

The oral manifestations and related mechanisms of COVID-19 caused by SARS-CoV-2 infection

Light as a Cure in COVID-19: A Challenge for Medicine

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