Could Pomegranate Fight against SARS-CoV-2?

Abstract

Pomegranate, Punica granatum L., is an authentic, generous fruit which is cultivated in many parts of the world for thousand years. The divine fruit was born from nature to provide humanity with its effluent benefits for life and health. Through the ages, Pomegranate occupied an eminent place in ayurvedic medicine. It was prescribed for treatment of parasitic infection, diarrhea, and ulcers. Pomegranate wealth of prolific pharmacological activities makes it a rich culture for multiple studies in recent years. It will not be surprising if Pomegranate provides humans with a possible help in SARS-CoV-2 pandemic. The enemy that has raided the world since the end of 2019.

Complementary and Alternative Medicine in COVID-19 Infection, an Old Weapon against a New Enemy

“…Treatment of SARS-CoV-2 has two pathways: the first is to overcome the viral infection either by blocking cell binding, replication, or direct viral effect on tissues. The second pathway is to counteract the overwhelming viral-induced immune response [25]. For blocking viral entry, many agents coexist, such as umifenovir [26,27], soluble recombinant hACE2, and specific monoclonal antibodies [28,29].…”

“…Its pharmacological activities are mediated mainly by phenolic compounds [67]. Anti-viral action is demonstrated against many viruses [25,68,69]. The immune modulation activity of pomegranate was illustrated in several studies.…”