Could interallelic interactions be a key to the epigenetic aspects of fitness-trait inbreeding depression?

Biémont, Christian; Vieira, Cristina

doi:10.1038/hdy.2013.80

Cited by 3 publications

(2 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, translocating adults, juveniles or eggs to predator-free environments has also been a key strategy for all five kiwi species, and translocations are currently increasing in importance (Colbourne 2005, Innes et al 2016, Kiwis for Kiwi 2016, Germano et al 2018. Predicting successful translocation outcomes that involve genetic rescue requires detailed information about the genetic and epigenetic variation of the target as well as the source populations (Groszmann et al 2013, Bi emont & Vieira 2014, vonHoldt et al 2018, Rey et al 2020. Decisionmaking in the absence of this information risks leading to management strategies that are insufficient or even harmful for future population sustainability.…”

Section: Discussionmentioning

confidence: 99%

Gaps in genetic knowledge affect conservation management of kiwi (Apteryx) species

Undin

Hills

Lockhart

et al. 2021

Ibis

View full text Add to dashboard Cite

Worldwide, there is growing appreciation of the importance of integrating genetic information into conservation management. However, there are commonly occurring problems which impact on doing this successfully. This issue is well illustrated by kiwi Apteryx species. Like many endangered taxa, extant kiwi populations are small, fragmented and isolated, raising concerns of potential inbreeding depression. Accordingly, kiwi conservation includes discussion of genetic management and translocations. To date, kiwi taxa have been the subject of 41 genetic studies. Here we provide the first synthesized review of these studies. We conclude that despite the impressive study effort, current understanding of kiwi genetics is insufficient to guide genetic management, predict translocation outcomes and manage biological diversity to achieve future sustainability of the species. We explain why, and outline research questions that can be addressed with new genome science technologies. Using new technologies to build on the foundation of work already undertaken, we see a great opportunity to address key issues for North Island Brown Kiwi Apteryx mantelli that are central to the conservation concerns for many threatened species. Specifically, we suggest that historical, disjunct, mainland populations combined with translocations of North Island Brown Kiwi to offshore islands have generated unique case studies to investigate the effects of fragmentation, cessation of gene flow, inbreeding, outbreeding and hybridization on biological diversity.

show abstract

Section: Discussionmentioning

confidence: 99%

Gaps in genetic knowledge affect conservation management of kiwi (Apteryx) species

Undin

Hills

Lockhart

et al. 2021

Ibis

View full text Add to dashboard Cite

show abstract

“…While our understanding of diversity, resilience and the contrasting outcomes of hybridization is informed by genetic variation, the importance of epigenetic variation is increasingly being recognized (Cheptou and Donohue, 2013;Groszmann et al, 2013;Biémont and Vieira, 2014). Epigenetic changes accompanying environmental change play a key role in plastic responses that occur at a faster rate than mutational change and the sorting of allelic variation (Hochholdinger and Baldauf, 2018;Miryeganeh and Saze, 2019;Rey et al, 2020).…”

Section: Assessing Biodiversitymentioning

confidence: 99%

Genetic Rescue and the Plight of Ponui Hybrids

Undin¹,

Lockhart²,

Hills³

et al. 2021

Front. Conserv. Sci.

View full text Add to dashboard Cite

Long-term sustainable and resilient populations is a key goal of conservation. How to best achieve this is controversial. There are, for instance, polarized views concerning the fitness and conservation value of hybrid populations founded through multi-origin translocations. A classic example concerns Apteryx (kiwi) in New Zealand. The A. mantelli of Ponui Island constitute a hybrid population where the birds are highly successful in their island habitat. A key dilemma for managers is understanding the reason for this success. Are the hybrid birds of Ponui Island of “no future conservation value” as recently asserted, or do they represent an outstanding example of genetic rescue and an important resource for future translocations? There has been a paradigm shift in scientific thinking concerning hybrids, but the ecological significance of admixed genomes remains difficult to assess. This limits what we can currently predict in conservation science. New understanding from genome science challenges the sufficiency of population genetic models to inform decision making and suggests instead that the contrasting outcomes of hybridization, “outbreeding depression” and “heterosis,” require understanding additional factors that modulate gene and protein expression and how these factors are influenced by the environment. We discuss these findings and the investigations that might help us to better understand the birds of Ponui, inform conservation management of kiwi and provide insight relevant for the future survival of Apteryx.

show abstract

Genomic methylation and transcriptomic profiling provides insights into heading depression in inbred Brassica rapa L. ssp. pekinensis

Liu

Cui

Tang

et al. 2018

Gene

View full text Add to dashboard Cite

Inbreeding depression is the reduction in fitness observed in inbred populations. In plants, it leads to disease, weaker resistance to adverse environmental conditions, inhibition of growth, and decrease of yield. To elucidate molecular mechanisms behind inbreeding depression, we compared global DNA methylation and transcriptome profiles of a normal and a highly inbred heading degenerated variety of the Chinese cabbage (Brassica rapa L. ssp. pekinensis). DNA methylation was reduced in inbred plants, suggesting a change in the epigenetic landscape. Transcriptome analysis by RNA-Seq revealed that genes in auxin-response and synthesis pathways were differentially expressed in the inbreeding depression lines. Interestingly, methylation levels of some of those genes were also changed. Furthermore, endogenous IAA content was decreased in inbred plants, in agreement with expression and methylation data. Chemical inhibition of auxin also replicated the degenerated phenotype in normal plants, while exogenous IAA application had no effect in inbred depression plants, suggesting a more complex mechanism. These data indicate DNA methylation-regulated auxin pathways play a role in establishing inbred depression phenotypes in plants. Our findings reveal new insights into inbreeding depression and leafy head development in Chinese cabbage.

show abstract

Could interallelic interactions be a key to the epigenetic aspects of fitness-trait inbreeding depression?

Cited by 3 publications

References 21 publications

Gaps in genetic knowledge affect conservation management of kiwi (Apteryx) species

Gaps in genetic knowledge affect conservation management of kiwi (Apteryx) species

Genetic Rescue and the Plight of Ponui Hybrids

Genomic methylation and transcriptomic profiling provides insights into heading depression in inbred Brassica rapa L. ssp. pekinensis

Contact Info

Product

Resources

About