Could foodomics hold the key to unlocking the role of prebiotics in gut microbiota and immunity?

Relationship between Dietary Polyphenols and Gut Microbiota: New Clues to Improve Cognitive Disorders, Mood Disorders and Circadian Rhythms

“…G-protein-coupled receptors enhance IL-10 secretion in the antigen-specific Th1 cells of mice with colitis, thereby reducing neuroinflammation [ 95 ]. Most plant polyphenols enter the body and interact directly with the intestinal flora in both directions, influencing the development of the intestinal and nervous systems and improving the function of the intestinal barrier and BBB [ 96 ]. Various natural plant ingredients also act on the intestinal flora to maintain the stability of the nervous system.…”

Editorial: Application of omics-based technologies and the impact on food science

“…In this respect, metabolomics combined with other omics technologies is of great interest in identifying biologically active compounds (Nayak et al, 2021). Additionally, studies regarding interactions between intestinal beneficial microorganisms and food compounds have revealed new sources of prebiotics (That et al, 2022); and novel probiotic microorganisms as well as their functional mechanisms have been determined through omics data analyses, and these can be further investigated for developing fermented foods with functional properties (Khullar et al, 2022).…”