Could Anticoagulation or Antiaggregation Treatment Be Ceased in Patients With Primary Antiphospholipid Syndrome When Antiphospholipid Antibodies Become Persistently Negative?

The growing role of precision medicine for the treatment of autoimmune diseases; results of a systematic review of literature and Experts’ Consensus

“…None of these patients were included in our analysis due to the lack of data. Overall, only 20 patients (from 3 studies) [145,146,149] were included in the final analysis. These patients had primary APS, received initial treatment with OAC, which was subsequently withdrawn after persistent negativization of their aPL titre.…”