“…The dose varied usually between 0.8 and 1.2 g. daily, but was increased in some cases to 1.6 g. a day. The absence of side-effects was stressed by Gordonoff and Kramer (1949), although they comment on the undesirable side-effects of the hydantoins as a group. Janz (1953) found anirrit most effective in the treatment of purely major epilepsy and inadequate in the control of minor and minimal epilepsy.…”