Cotton-wool spots in patients with migraine

Yuan, Po Hsiang Shawn; Micieli, Jonathan A.

doi:10.1016/j.jcjo.2021.11.006

Cited by 1 publication

(2 citation statements)

References 5 publications

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“…Although PAMM and CWS have been independently linked to migraine in the literature, to the best of our knowledge, the three occurring simultaneously have not been described. 7,8…”

Section: Discussionmentioning

confidence: 99%

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Paracentral acute middle maculopathy and cotton wool spots in a patient with ocular migraine: A case report

Hall,

Maleki

2024

European Journal of Ophthalmology

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In this study, we report paracentral acute middle maculopathy (PAMM) and cotton wool spots (CWS) in a patient with ocular migraine. A 74-year-old man presented with persistent paracentral scotoma in the right eye that began a week prior. His visual acuity was 20/25 in the right eye and 20/40 in the left. Dilated fundoscopy revealed CWS in the right eye. Spectral-domain optical coherence tomography (SD-OCT) showed hyper-reflective bands in the inner nuclear layer corresponding to parafoveal lesions seen on near-infrared imaging in the right eye consistent with the diagnosis of PAMM. Further laboratory studies were unremarkable, and a transthoracic echocardiogram and a carotid ultrasound were unrevealing. The patient was started on brimonidine three times daily in both eyes. The patient reported subjective improvement in the paracentral scotoma and the absence of ocular migraine symptoms at two-month follow-up. We conclude from this case that PAMM and CWS can occur simultaneously in ocular migraine, and we suggest that retinal vascular changes associated with ocular migraine may contribute to ischemia underlying both entities. Additionally, we suggest a potential therapy in brimonidine due to its proposed beneficial effects on retinal vasculature and neuroprotection.

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“…Although PAMM and CWS have been independently linked to migraine in the literature, to the best of our knowledge, the three occurring simultaneously have not been described. 7,8…”

Section: Discussionmentioning

confidence: 99%

“…Although PAMM and CWS have been independently linked to migraine in the literature, to the best of our knowledge, the three occurring simultaneously have not been described. 7,8 Our patient had a history of migraine headaches with aura in the past. He experienced sparkles in his vision a week before the scotoma.…”

Section: Np40mentioning

confidence: 96%

Paracentral acute middle maculopathy and cotton wool spots in a patient with ocular migraine: A case report

Hall,

Maleki

2024

European Journal of Ophthalmology

View full text Add to dashboard Cite

show abstract

Cotton-wool spots in patients with migraine

Cited by 1 publication

References 5 publications

Paracentral acute middle maculopathy and cotton wool spots in a patient with ocular migraine: A case report

Paracentral acute middle maculopathy and cotton wool spots in a patient with ocular migraine: A case report

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