Costs of nosocomial infection in a neonatal unit

Girard, R.; Fabry, J.; Meynet, R.; Lambert, Dominique; Sepetjan, M.

doi:10.1016/0195-6701(83)90006-3

Cited by 26 publications

(8 citation statements)

References 8 publications

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“…The control variables were selected by reviewing the literature and identifying important determinants of hospital costs [8][9][10][11][27][28][29][30][31][32][33][34][35][36][37][38]. The complete sets of variables that were available and used in the analysis are presented in Table 1 and the summary statistics on a subset of important variables are presented in Table 2.…”

Section: Data and Model Speci¢cationmentioning

confidence: 99%

Correcting for bias when estimating the cost of hospital-acquired infection: an analysis of lower respiratory tract infections in non-surgical patients

Graves¹,

Weinhold²,

Roberts³

2005

Health Econ.

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Hospital acquired infections (HAI) are costly but many are avoidable. Evaluating prevention programmes requires data on their costs and benefits. Estimating the actual costs of HAI (a measure of the cost savings due to prevention) is difficult as HAI changes cost by extending patient length of stay, yet, length of stay is a major risk factor for HAI. This endogeneity bias can confound attempts to measure accurately the cost of HAI. We propose a two-stage instrumental variables estimation strategy that explicitly controls for the endogeneity between risk of HAI and length of stay. We find that a 10% reduction in ex ante risk of HAI results in an expected savings of pound 693 ($ US 984).

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Section: Data and Model Speci¢cationmentioning

confidence: 99%

Correcting for bias when estimating the cost of hospital-acquired infection: an analysis of lower respiratory tract infections in non-surgical patients

Graves¹,

Weinhold²,

Roberts³

2005

Health Econ.

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“…After the occurrence of the outbreak the difference was 4 days. Some published studies in neonates revealed an average extra stay of 24 days, 14 6.7 days, 22 and 5.2 days. 23 The differentiation of results may be related to several possible reasons.…”

Section: Discussionmentioning

confidence: 98%

“…First, in some studies, neonates were followed until discharge from NICU 14 and in other studies neonates were followed from the unit. 22,23 The neonates of in the present study were followed until discharged from the hospital. Secondly, there may be different discharge criteria for transfer to a low care unit.…”

Section: Discussionmentioning

confidence: 99%

Salmonella typhimurium outbreak in a neonatal unit in Turkey

et al. 2009

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“…3 NI has also been reported to increase the length of stay and hospital charges, [29][30][31][32][33] and has been associated with greater degrees of various morbidities. Hence, prevention of NIs in VLBW infants might reasonably be expected to improve the outcome of these vulnerable infants.…”

Section: Discussionmentioning

confidence: 99%

Early neutropenia is not associated with an increased rate of nosocomial infection in very low-birth-weight infants

et al. 2008

J Perinatol

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Background: Evidence is contradictory whether very low-birth-weight (VLBW, birth weight <1500 g) infants with early neutropenia (NP), especially those born to mothers with preeclampsia experience a greater incidence of nosocomial infection (NI).Objective: To investigate whether NP within the first 7 days of life is a risk factor for NI in VLBW infants.Methods: Over a 42-month period, we identified all VLBW infants born at p34 weeks gestation who survived for more than 72 h. Infants who had no evidence of early infection, who had at least one complete blood count performed in the first week of life, and who were not given prophylactic recombinant human granulocyte colony-stimulating factor (rhG-CSF) were included in this retrospective study. Early NP was defined as an absolute neutrophil count less than 1500 per ml at any time during the first week of life. NI was defined as the culture of a bacterial or fungal pathogen from a sterile body fluid that was obtained after 72 h of life in an infant with one or more clinical signs of infection.Results: A total of 338 VLBW infants were reviewed. Of those, 51 infants were excluded because of death or onset of an infection before 72 h of age, lack of a complete blood count in the first week of life or treatment with rhG-CSF. Of the remaining 287 infants, NI occurred in 11 of 77 (14.3%) infants with early NP compared to 42 of 210 (20.0%) infants without early NP (P ¼ 0.31). Infants who developed NI were smaller and less mature, had lower Apgar scores, were more frequently instrumented with central lines and required a longer duration of parenteral nutrition compared to infants without NI. Infants with NI also had a higher mortality and a greater incidence of necrotizing enterocolitis, severe intraventricular hemorrhage and threshold retinopathy of prematurity. However, using stepwise multivariate logistic regression analysis, only the duration of parenteral nutrition and gestational age were significant risk factors for NI.

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Costs of nosocomial infection in a neonatal unit

Cited by 26 publications

References 8 publications

Correcting for bias when estimating the cost of hospital-acquired infection: an analysis of lower respiratory tract infections in non-surgical patients

Correcting for bias when estimating the cost of hospital-acquired infection: an analysis of lower respiratory tract infections in non-surgical patients

Salmonella typhimurium outbreak in a neonatal unit in Turkey

Early neutropenia is not associated with an increased rate of nosocomial infection in very low-birth-weight infants

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