Costing Dengue Fever Cases and Outbreaks: Recommendations from a Costing Dengue Working Group in the Americas

Constenla, Dagna; Armién, Blas; Arredondo, Juan Camilo; Carabalí, Mabel; Carrasquilla, Gabriel; Castro, R Diego Fernando; Durand, Laure; Durán-Arenas, Luis; García, María Elena; Gallegos, Rivera Verónica; Gontes, Maria Luisa; López, Juan Guillermo; McFarlane, Charlton; Montoya, Romeo; Sartori, Ana Marli Christovam; Siqueira, João Bosco; Martelli, Celina Maria Turchi

doi:10.1016/j.vhri.2015.06.001

Cited by 15 publications

(15 citation statements)

References 12 publications

(18 reference statements)

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“…In line with systematic literature reviews, 25,28,29 we also found a wide range of costs and costing approaches for similar interventions 14,18,20,21 (Table 5 ). In addition, although our estimates for Brazil, Ecuador (CPSC) and Uruguay are within those ranges, the cost estimates for Colombia and Mexico are considerably higher due to the costs of installing LLINs using metallic frames, which none of the previous studies have done.…”

Section: Resultssupporting

confidence: 84%

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Innovative dengue vector control interventions in Latin America: what do they cost?

Alfonso-Sierra

Basso

Beltrán-Ayala

et al. 2016

Pathogens and Global Health

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Background: Five studies were conducted in Fortaleza (Brazil), Girardot (Colombia), Machala (Ecuador), Acapulco (Mexico), and Salto (Uruguay) to assess dengue vector control interventions tailored to the context. The studies involved the community explicitly in the implementation, and focused on the most productive breeding places for Aedes aegypti. This article reports the cost analysis of these interventions. Methods: We conducted the costing from the perspective of the vector control program. We collected data on quantities and unit costs of the resources used to deliver the interventions. Comparable information was requested for the routine activities. Cost items were classified, analyzed descriptively, and aggregated to calculate total costs, costs per house reached, and incremental costs. Results: Cost per house of the interventions were $18.89 (Fortaleza), $21.86 (Girardot), $30.61 (Machala), $39.47 (Acapulco), and $6.98 (Salto). Intervention components that focused mainly on changes to the established vector control programs seem affordable; cost savings were identified in Salto (−21%) and the clean patio component in Machala (−12%). An incremental cost of 10% was estimated in Fortaleza. On the other hand, there were also completely new components that would require sizeable financial efforts (installing insecticide-treated nets in Girardot and Acapulco costs $16.97 and $24.96 per house, respectively). Conclusions: The interventions are promising, seem affordable and may improve the cost profile of the established vector control programs. The costs of the new components could be considerable, and should be assessed in relation to the benefits in reduced dengue burden.

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Section: Resultssupporting

confidence: 84%

“…Resource items were classified following the cost components proposed in the literature 25,26 and previous cost analysis of similar interventions. 18 Thus, we classified first on recurrent costs (personnel, consumables, and other recurrent costs) and capital costs.…”

Section: Methods and Study Settingsmentioning

confidence: 99%

Innovative dengue vector control interventions in Latin America: what do they cost?

Alfonso-Sierra

Basso

Beltrán-Ayala

et al. 2016

Pathogens and Global Health

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“…The comparability of the reviewed studies was restricted due to variations in the perspective taken, what cost items were included, as well as how the results were reported [39] . To improve the comparability of different studies, guidelines for estimating dengue-related costs have been proposed 39 , 47 . It would also be beneficial if future studies clearly report the exchange rates used, the year of the prices, and specifically state the approach used to adjust for inflation [48] .…”

Section: Data Gaps and Future Research Needsmentioning

confidence: 99%

The Estimates of the Health and Economic Burden of Dengue in Vietnam

Hung

Clapham

Bettis

et al. 2018

Trends in Parasitology

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Dengue has been estimated to cause a substantial health and economic burden in Vietnam. The most recent studies have estimated that it is responsible for 39 884 disability-adjusted life years (DALYs) annually, representing an economic burden of US$94.87 million per year (in 2016 prices). However, there are alternative burden estimates that are notably lower. This variation is predominantly due to differences in how the number of symptomatic dengue cases is estimated. Understanding the methodology of these burden calculations is vital when interpreting health economic analyses of dengue. This review aims to provide an overview of the health and economic burden estimates of dengue in Vietnam. We also highlight important research gaps for future studies.

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“…The indirect costs are those associated with the loss in productivity from illness and death [ 103 ]. A robust assessment of the economic burden helps to i) identify information gaps, research needs, and refinements to the national statistical reporting systems; ii) argue that policies on dengue control and prevention should be given a high priority on the public health policy agenda; and iii) provide a baseline measure to determine the cost effectiveness of dengue policies and programs [ 104 ]. However, few studies have assessed the economic burden of dengue [ 105 ].…”

Section: Relative Burden Of Dengue In Selected Hicsmentioning

confidence: 99%

Public Health Responses to and Challenges for the Control of Dengue Transmission in High-Income Countries: Four Case Studies

et al. 2016

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Dengue has a negative impact in low- and lower middle-income countries, but also affects upper middle- and high-income countries. Despite the efforts at controlling this disease, it is unclear why dengue remains an issue in affluent countries. A better understanding of dengue epidemiology and its burden, and those of chikungunya virus and Zika virus which share vectors with dengue, is required to prevent the emergence of these diseases in high-income countries in the future. The purpose of this review was to assess the relative burden of dengue in four high-income countries and to appraise the similarities and differences in dengue transmission. We searched PubMed, ISI Web of Science, and Google Scholar using specific keywords for articles published up to 05 May 2016. We found that outbreaks rarely occur where only Aedes albopictus is present. The main similarities between countries uncovered by our review are the proximity to dengue-endemic countries, the presence of a competent mosquito vector, a largely nonimmune population, and a lack of citizens’ engagement in control of mosquito breeding. We identified important epidemiological and environmental issues including the increase of local transmission despite control efforts, population growth, difficulty locating larval sites, and increased human mobility from neighboring endemic countries. Budget cuts in health and lack of practical vaccines contribute to an increased risk. To be successful, dengue-control programs for high-income countries must consider the epidemiology of dengue in other countries and use this information to minimize virus importation, improve the control of the cryptic larval habitat, and engage the community in reducing vector breeding. Finally, the presence of a communicable disease center is critical for managing and reducing future disease risks.

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Costing Dengue Fever Cases and Outbreaks: Recommendations from a Costing Dengue Working Group in the Americas

Abstract: The current guideline is the result of constructive collaboration among a multidisciplinary research team to better ascertain the true economic burden of dengue across countries of the region.

Cited by 15 publications

References 12 publications

Innovative dengue vector control interventions in Latin America: what do they cost?

Innovative dengue vector control interventions in Latin America: what do they cost?

The Estimates of the Health and Economic Burden of Dengue in Vietnam

Public Health Responses to and Challenges for the Control of Dengue Transmission in High-Income Countries: Four Case Studies

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