“…The physical and psycho-emotional sequelae result not in endurance and resilience but rather in pain, financial burden, and other significant impacts on lifestyle ( Osterberg and Boivie, 2010 ; Arewasikporn et al., 2018 ; Ferraro et al., 2018 ; Young et al., 2017 ; Marck et al., 2017 ; Hakansson et al., 2019 ; Kratz et al., 2017 ; Amtmann et al., 2015 ; Benson and Kerr, 2014 ; Pinkston et al., 2007 ; Pinkston and Alekseeva, 2006 ; Shahrbanian et al., 2013 ; Kratz et al., 2017 , 2017 ; Harding et al., 2019 ). Typically, standard of care therapies for neurological disorders focus only on primary (physical/motor) symptoms, when it is actually the non-physical effects that have the greatest impact on quality of life ( Zivadinov et al., 2016 ; Tornatore et al., 2016 ; Kappos et al., 2015 ; Harel et al., 2018 ; Bovis et al., 2019 ; Sormani et al., 2019 ; Mattioli et al., 2014 ; Maruszczak et al., 2015 ). As such, there has recently been a concerted effort to better characterize the neuropsychological aspects of MS ( Benedict et al., 2017 ; Isernia et al., 2019 ; Migliore et al., 2019 ; Macias Islas and Ciampi, 2019 ; Di Stefano et al., 2019 ; Scherder et al., 2017 , 2018 ; Khan et al., 2018 ), including pain and cognitive, psychological, and social deficits, and to redefine them as essential aspects of MS pathology ( Arewasikporn et al., 2018 ; Ferraro et al., 2018 ; Young et al., 2017 ; Marck et al., 2017 ; Hakansson et al., 2019 ; Kratz et al., 2017 ; Kratz et al., 2017 , 2017 ; Newland et al., 2016 ; Benedict et al., 2017 ; Isernia et al., 2019 ; Chalah and Ayache, 2017 ; Lex et al., 2018 ).…”