Cost-Utility Analysis of Pharmaceutical Care Intervention Versus Usual Care in Management of Nigerian Patients with Type 2 Diabetes

Adibe, Maxwell Ogochukwu; Aguwa, C. N.; Ukwe, Chinwe Victoria

doi:10.1016/j.vhri.2013.06.009

Cited by 32 publications

(90 citation statements)

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“…Of the 30 articles included in the review , 21 were CEAs [16,[18][19][20][21][22][23][24][25][27][28][29][30][31][32][33][34][35][36][37]39], 4 were CUAs [17,26,38,40], 4 were CBAs [42][43][44][45], and 1 consisted of both CEA and CBA [41]. Among those studies, 7 were conducted in the United States [17,20,23,24,28,44,45], 9 in Europe [16,26,[31][32][33][34]37,41,43], 7 in Asia [25,27,29,30,35,…”

Section: Resultsmentioning

confidence: 99%

“…More than a half of the studies (n ¼ 17) conducted their economic analyses using the patient's perspective and at least one more perspectives such as societal (n ¼ 5) [21,25,31,40,41], government or payer (n ¼ 5) [28,30,31,34,40], and health care provider, for example, health system, hospital, or clinic (n ¼ 11) [16][17][18][19][21][22][23][24]27,29,41]. Trial analysis was the most frequently used methodology (n ¼ 16) [20,23,26,27,[29][30][31][32][33][36][37][38][39][40]42,44], followed by decision-tree model (n ¼ 5) [16,17,25,28,34] and observational analysis (n ¼ 5) [19,[21][22][23]35,41,…”

Section: Resultsmentioning

confidence: 99%

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A Systematic Review of Health Economic Evaluation Studies Using the Patient’s Perspective

Tai

Bae

2016

Value in Health

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There is a paucity of health economic evaluations conducted from the patient's perspective in the literature. For those studies using the patient's perspective, the true patient costs were not fully explored and study reporting quality was not optimal. With the increasing focus on patient-centered outcomes in health policy research, more frequent use of the patient's perspective in economic studies should be advocated.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

A Systematic Review of Health Economic Evaluation Studies Using the Patient’s Perspective

Tai

Bae

2016

Value in Health

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“…From the perspective of health economics, health-related QoL (HRQoL) is an important patient-reported outcome useful for the purpose of understanding the burden of chronic diseases such as diabetes [ 15 ]. HRQoL measures are useful in evaluating the efficacy, cost effectiveness, and net benefits of current healthcare programs and interventions [ 16 ], and have been found to be relevant in the economic evaluation of the cost effectiveness of buprenorphine patch in the management of moderate pain [ 17 ], early versus late total hip replacement [ 18 ], and in the comparison of intensive against conventional education and supervision for the self-management of asthmatic [ 19 ] and diabetic patients [ 20 ]. At present, several multi-attribute utility instruments (MAUIs) have been developed and used for the purpose of determining HRQoL in principle.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Health Status of Type 2 Diabetes Outpatients Receiving Care in a Tertiary Hospital in Nigeria

Adibe

Anosike

Nduka

et al. 2017

PharmacoEconomics Open

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ObjectivesThe aim of this study was to determine the health status of type 2 diabetes patients in a Nigerian tertiary hospital, and examine the sociodemographic and clinical variables that predicted the health status of type 2 diabetes patients in terms of utility valuations and EuroQol Visual Analogue Scale (EQ-VAS) score.MethodsThis was a cross-sectional study of 147 diabetes patients attending the University of Nigeria Teaching Hospital, Enugu State, Nigeria. The EQ-5D-5L instrument, version 2.1, was used to evaluate patients’ self-reported health status, and patients who gave informed consent completed the questionnaire while waiting to see a doctor. Descriptive and multiple linear regression analyses were performed using SPSS version 20.ResultsOverall, 147 patients participated in this study, with a mean age (± standard deviation) of 56.7 years (± 10.33). Over half of the respondents were females (55.1%) and more than half were older than 60 years of age. The mean EQ-VAS and utility valuations of respondents were 72.59 ± 10.51 and 0.72 ± 0.13, respectively. The age of respondents independently and significantly predicted EQ-VAS by −2.659 per year, while the age of respondents, level of education, duration of diabetes, and presence of other illnesses independently and significantly predicted utility valuations by −0.020 per year, +0.029 per level of education, −0.008 per year, and −0.044 per illness, respectively. Less than 39% of patients experienced no problems for each of the dimensions, except self-care (68%).ConclusionThe results of this study revealed a relatively low health status among type 2 diabetic patients in Nigeria. Old age, duration of diabetes and the presence of other illnesses were major contributors to the negative impact on health status, while a higher level of education contributed positively to health status. Adequate family support, as well as regular and effective patient counseling and education, may be worthwhile.Electronic supplementary materialThe online version of this article (doi:10.1007/s41669-017-0056-x) contains supplementary material, which is available to authorized users.

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“…In developing countries with poorer health care systems, the cost of managing DM is considerable. In a recent randomized, controlled trial (RCT) in Nigeria, Adibe et al showed that pharmaceutical intervention with a multidisciplinary approach cost 8 8,525 Nigerian naira (571 US dollars) per quality-adjusted life years gained 4. Although this was 95% more cost effective compared with usual care (incremental cost of 10,623 Nigerian naira or 69 US dollars), it still represents a significant financial burden in a country where 68% of the population live below the international poverty line of 1.25 US dollars per day 5…”

Section: Introductionmentioning

confidence: 99%

Holistic approach to prevention and management of type 2 diabetes mellitus in a family setting

Ofori¹,

Unachukwu²

2014

DMSO

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Diabetes mellitus (DM) is a chronic, progressive metabolic disorder with several complications that affect virtually all the systems in the human body. Type 2 DM (T2DM) is a major risk factor for cardiovascular disease (CVD). The management of T2DM is multifactorial, taking into account other major modifiable risk factors, like obesity, physical inactivity, smoking, blood pressure, and dyslipidemia. A multidisciplinary team is essential to maximize the care of individuals with DM. DM self-management education and patient-centered care are the cornerstones of management in addition to effective lifestyle strategies and pharmacotherapy with individualization of glycemic goals. Robust evidence supports the effectiveness of this approach when implemented. Individuals with DM and their family members usually share a common lifestyle that, not only predisposes the non-DM members to developing DM but also, increases their collective risk for CVD. In treating DM, involvement of the entire family, not only improves the care of the DM individual but also, helps to prevent the risk of developing DM in the family members.

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Cost-Utility Analysis of Pharmaceutical Care Intervention Versus Usual Care in Management of Nigerian Patients with Type 2 Diabetes

Abstract: The PC intervention was very cost-effective among patients with type 2 diabetes at the NGN 88,525 ($571.13) per QALY gained threshold, although considerable uncertainty surrounds these estimates.

Cited by 32 publications

References 18 publications

A Systematic Review of Health Economic Evaluation Studies Using the Patient’s Perspective

A Systematic Review of Health Economic Evaluation Studies Using the Patient’s Perspective

Evaluation of Health Status of Type 2 Diabetes Outpatients Receiving Care in a Tertiary Hospital in Nigeria

Holistic approach to prevention and management of type 2 diabetes mellitus in a family setting

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