Cost of Purchased Versus Produced Plasma from Donor Recruitment Through Transfusion

Prioli, Katherine M.; Pizzi, Laura T.; Karp, Julie Katz; Galanis, Taki; Herman, Jay H.

doi:10.1007/s40258-016-0255-0

Cited by 2 publications

(2 citation statements)

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“…Based on survey results and input from transfusion medicine experts (JKK and JHH) and the independent review panel, most tasks in the model are assumed to be performed by a hospital Blood Bank Technician or Technologist, with a base-case wage rate of US$24.91/h [ 23 ], based on the mean hourly wage rate for a Blood Bank Technician/Technologist per the Bureau of Labor Statistics (BLS), and a fringe benefits rate of 34.3% per BLS [ 24 ]. Per our prior research [ 25 ], select transfusion-related tasks are assumed to be performed by a nurse (e.g. performing and monitoring transfusion) or physician (e.g.…”

Section: Methodsmentioning

confidence: 99%

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Economic Implications of Pathogen Reduced and Bacterially Tested Platelet Components: A US Hospital Budget Impact Model

Prioli

Karp

Lyons

et al. 2018

Appl Health Econ Health Policy

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BackgroundUS FDA draft guidance includes pathogen reduction (PR) or secondary rapid bacterial testing (RT) in its recommendations for mitigating risk of platelet component (PC) bacterial contamination. An interactive budget impact model was created for hospitals to use when considering these technologies.MethodsA Microsoft Excel model was built and populated with base-case costs and probabilities identified through literature search and a survey of US hospital transfusion service directors. Annual costs of PC acquisition, testing, wastage, dispensing/transfusion, sepsis, shelf life, and reimbursement for a mid-sized hospital that purchases all of its PCs were compared for four scenarios: 100% conventional PCs (C-PC), 100% RT-PC, 100% PR-PC, and 50% RT-PC/50% PR-PC.ResultsAnnual total costs were US$3.64, US$3.67, and US$3.96 million when all platelets were C-PC, RT-PC, or PR-PC, respectively, or US$3.81 million in the 50% RT-PC/50% PR-PC scenario. The annual net cost of PR-PC, obtained by subtracting annual reimbursements from annual total costs, is 6.18% above that of RT-PC. Maximum usable shelf lives for C-PC, RT-PC, and PR-PC are 3.0, 5.0, and 3.6 days, respectively; hospitals obtain PR-PC components earliest at 1.37 days.ConclusionThe model predicts minimal cost increase for PR-PC versus RT-PC, including cost offsets such as elimination of bacterial detection and irradiation, and reimbursement. Additional safety provided by PR, including risk mitigation of transfusion-transmission of a broad spectrum of viruses, parasites, and emerging pathogens, may justify this increase. Effective PC shelf life may increase with RT, but platelets can be available sooner with PR due to elimination of bacterial detection, depending on blood center logistics.

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Section: Methodsmentioning

confidence: 99%

“…This model assumes all tasks for the dispensation of platelets for transfusion are performed by a hospital Blood Bank Technician/Technologist, with the exception of platelet ordering (performed by the floor physician) and delivery of platelets to the floor (via pneumatic tube) [ 25 ].…”

Section: Methodsmentioning

confidence: 99%