Cost implication of inpatient care of chronic kidney disease patients in a tertiary hospital in Southwest Nigeria

Adejumo, Oluseyi Ademola; Akinbodewa, Akinwumi Ayodeji; Ogunleye, A.; Enikuomehin, Adenike; Lawal, Olutoyin Morenike

doi:10.4103/1319-2442.279942

Cited by 10 publications

(9 citation statements)

References 9 publications

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“…Majority of HD patients in Nigeria are not optimally dialysed due to financial cost of RRT which is beyond their reach 31 32. Suboptimal dialysis may contribute to higher prevalence of poor sleep quality in MHD patients in this study which is similar to a report by Terzi et al 33.…”

Section: Discussionsupporting

confidence: 80%

Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study

Adejumo,

Edeki,

Mamven

et al. 2023

BMJ Open

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ObjectivePoor sleep quality adversely affects the overall well-being and outcomes of patients with chronic kidney disease (CKD). However, it has not been well studied in Africans with CKD. We determined the prevalence of poor sleep quality and associated factors among patients with CKD.DesignThis was a cross-sectional study that involved patients with CKD .SettingsThe study was carried out in the outpatient clinic of nine hospitals in Nigeria.MethodsSleep quality, depressive and anxiety symptoms and quality of life (QoL) were assessed among 307 patients with CKD using Pittsburgh Sleep Quality Index Questionnaire, Hospital Anxiety Depression Scale Questionnaire and 12-item Short Form Health Survey Quality of Life Questionnaire, respectively. The prevalence of poor sleep quality and associated factors were determined. A p<0.05 was considered as statistically significant.ResultsThe mean age of the study participants was 51.40±15.17 years. The male:female ratio was 1.5:1 One hundred and twenty-one (39.4%) of the patients were on maintenance haemodialysis (MHD). The prevalence of poor sleep quality, anxiety symptoms and depressive symptoms among the patients was 50.2%, 37.8% and 17.6%, respectively. The prevalence of poor sleep quality in the CKD stages 3, 4, 5 and 5D was 38.1%, 42.6%, 52.2% and 58.7%, respectively. The prevalence of poor sleep quality was significantly higher in MHD patients compared with predialysis CKD (59.5% vs 43.6%; p=0.008). Factors associated with poor sleep quality were CKD stage (p=0.035), anaemia (p=0.003), pruritus (p=0.045), anxiety symptoms (p≤0.001), depressive symptoms (p≤0.001) and reduced QoL (p≤0.001). On multivariate analysis, factors associated with poor sleep were anxiety (AOR 2.19; 95% CI 1.27 to 3.79; p=0.005), anaemia (AOR 5.49; 95% CI 1.43 to 21.00;p=0.013) and reduced physical component of QoL (AOR 4.11; 95% CI 1.61 to 10.47; p=0.003).ConclusionPoor sleep quality is common among patients with CKD especially in the advanced stage. The significant factors associated with poor sleep quality were QoL, anaemia and anxiety symptoms. These factors should be adequately managed to improve the overall outcomes of patients with CKD.

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Section: Discussionsupporting

confidence: 80%

Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study

Adejumo,

Edeki,

Mamven

et al. 2023

BMJ Open

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“…Late presentation coupled with dearth of medical personnel, diagnostic and therapeutic equipment, medication and prohibitive cost of treatment, most of which is out of pocket, implies that patients with these diseases may already have a poor prognosis even without COVID-19 [30][31][32][33].…”

Section: Plos Onementioning

confidence: 99%

Outcomes of COVID-19 patients with comorbidities in southwest Nigeria

et al. 2021

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Background Data on the comorbidities that result in negative outcomes for people with COVID-19 are currently scarce for African populations. This study identifies comorbidities that predict death among a large sample of COVID-19 patients from Nigeria. Methods This was a retrospective analysis of medical records for 2184 laboratory confirmed cases of COVID-19 in Lagos, southwest Nigeria. Extracted data included age, sex, severity of condition at presentation and self-reported comorbidities. The outcomes of interest were death or discharge from facility. Results Most of the cases were male (65.8%) and the median age was 43 years (IQR: 33–55). Four hundred and ninety-two patients (22.5%) had at least one comorbidity and the most common amongst them were hypertension (74.2%) and diabetes (30.3%). The mortality rate was 3.3% and a significantly higher proportion of patients with comorbidities died compared to those with none. The comorbidities that predicted death were hypertension (OR: 2.21, 95%CI: 1.22–4.01), diabetes (OR: 3.69, 95% CI: 1.99–6.85), renal disease (OR: 12.53, 95%CI: 1.97–79.56), cancer (OR: 14.12, 95% CI: 2.03–98.19) and HIV (OR: 1.77–84.15]. Conclusion Comorbidities are prevalent and the associated risk of death is high among COVID-19 patients in Lagos, Nigeria. Public enlightenment, early identification and targeted care for COVID-19 cases with comorbidities are recommended as the pandemic evolves.

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“…Patients with different comorbidities have been presented to have a poor prognosis even without COVID-19 because of late presentation coupled with lack of medical professionals, diagnostic and therapeutic equipment, and exorbitant treatment costs [20][21][22][23]. Regarding comorbidities that anticipated death in COVID-19-infected intensive care patients, our study confirms the prior finding of Grasselli et al [11] and Osibogun et al [12] who had found that diabetes mellitus exacerbated COVID-19 progression, and patients with diabetes mellitus have succumbed to COVID-19.…”

Section: Comorbiditiesmentioning

confidence: 99%

Effect of risk factors on the outcomes of COVID-19-infected intensive care patients: a single-center retrospective study

Sapra

Jha

et al. 2022

jidhealth

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Background: To date, little attention has been paid to the impact of risk factors on the outcome of patients with coronavirus disease 2019 (COVID-19) hospitalized in the intensive care unit (ICU). This study was performed to examine the effects of risk factors on death among COVID-19 patients hospitalized in the ICU. Methods: From April 2020 to November 2020, data on 141 COVID-19-infected intensive care patients at 7 Air Force Hospital, Kanpur, were retrospectively retrieved. All analyses were performed using SPSS statistical software (SPSS Inc., Chicago, IL, USA, 15.0). Bivariate and multivariate logistic regression analysis was done to identify independent risk factors. A p-value <0.05 was considered statistically significant. Results: Most of study population were males (69.5%) with mean age of 59.8 ± 17.5 years. Out of 141 patients, 60 (42.6%) patients had comorbidities and 81 (57.4%) patients had no comorbidities. ICU death rates were 46.1%. Bivariate logistic regression analysis revealed that male sex (OR:0.45;95%CI:0.21-0.94), diabetes mellitus (OR:2.96; 95%CI:1.16-7.54), coronary artery disease (OR:2.48;95%CI:0.83-7.37), chronic kidney disease (OR:0.13,95% CI:0.02-1.12), patients with one (OR:1.25,95%CI:0.54-2.86) or more than two comorbidities (OR:1.95,95%CI:0.81-4.70), and who required high flow oxygen therapy (OR:13.30,95%CI:5.81-30.43), non-invasive (OR: 0.10,95% CI:0.02-0.45) and invasive ventilators (OR:0.04,95%CI:0.02-0.09) all were associated with higher ICU death rates. Multivariable logistic regression found following independent risk factors for death: patients with one comorbidity (OR:0.10;95%CI:0.02-0.66), non-invasive ventilator (OR:0.005;95%CI:0.000-0.091), and invasive ventilator (OR:0.003;95%CI:0.000-0.032). Conclusion: Identification of risk factors is of utmost importance to reduce death in COVID-19 infected intensive care patients.

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Cost implication of inpatient care of chronic kidney disease patients in a tertiary hospital in Southwest Nigeria

Cited by 10 publications

References 9 publications

Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study

Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study

Outcomes of COVID-19 patients with comorbidities in southwest Nigeria

Effect of risk factors on the outcomes of COVID-19-infected intensive care patients: a single-center retrospective study

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