Cost-Effectiveness of Korea's National Cervical Cancer Screening Program

Cho, Eun; Kang, Moon Hae; Choi, Kui Son; Suh, Mi Na; Jun, Jae Kwan; Park, Sohee

doi:10.7314/apjcp.2013.14.7.4329

Cited by 7 publications

(5 citation statements)

References 25 publications

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“…Globally, cervical cancer is a preventable cancer [ 1 ]. It is causally associated with infection with the oncogenic human papillomavirus (HPV), particularly the two most common strains, HPV 16 and 18 [ 2 - 4 ]. The development of various preventive strategies and clinical approaches has achieved a reduced incidence of cervical cancer, and hence mortality, in a number of developed countries [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Changing trends in the incidence (1999-2011) and mortality (1983-2013) of cervical cancer in the Republic of Korea

Park¹,

Vongdala²,

Kim³

et al. 2015

Epidemiol Health

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Cervical cancer is a well-known preventable cancer worldwide. Many countries including Korea have pursued the positive endpoint of a reduction in mortality from cervical cancer. Our aim is to examine changing trends in cervical cancer incidence and mortality after the implementation of a national preventive effort in Korea. Cervical cancer incidence data from 1999 to 2011 and mortality data from 1983 to 2013 were collected from the Korean Statistical Information Service. Yearly age-standardized rates (ASR) per 100,000 were compared using two standards: the 2005 Korean population and the world standard population, based on Segi’s world standard for incidence and the World Health Organization for mortality. In Korea, the age-standardized incidence of cervical cancer per 100,000 persons declined from 17.2 in 2000 to 11.8 in 2011. However, the group aged 25 to 29 showed a higher rate in 2011 (ASR, 6.5) than in 2000 (ASR, 3.6). The age-standardized mortality rate per 100,000 persons dropped from 2.81 in 2000 to 1.95 in 2013. In the worldwide comparison, the incidence rates remained close to the average incidence estimate of more developed regions (ASR, 9.9). The decreasing mortality trend in Korea approached the lower rate observed in Australia (ASR, 1.4) in 2010. Although the incidence rate of cervical cancer is continuously declining in Korea, it is still high relative to other countries. Moreover, incidence and mortality rates in females aged 30 years or under have recently increased. It is necessary to develop effective policy to reduce both incidence and mortality, particularly in younger age groups.

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Section: Introductionmentioning

confidence: 99%

Changing trends in the incidence (1999-2011) and mortality (1983-2013) of cervical cancer in the Republic of Korea

Park¹,

Vongdala²,

Kim³

et al. 2015

Epidemiol Health

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“…Population-based screening programs can reduce the risk of developing advanced cervical cancer and associated deaths (Sankaranarayanan et al, 2009;Sherris et al, 2009). This approach is also feasible for the second prevention of colorectal cancer and female breast cancer (Mandel et al, 1993;Anderson et al, 2008;Zauber et al, 2008;Atkin et al, 2010), but all the screening programs should be proposed according to local economic and social conditions, and evaluated by cost-effectiveness analysis (Cho et al, 2013;Ito et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

Mortality of Major Cancers in Guangxi, China: Sex, Age and Geographical Differences from 1971 and 2005

Deng¹,

Long²,

Li³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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The incidence and mortality rates of liver and nasopharyngeal cancer in Guangxi province of China have always been among the highest in the world, and cancer is one of the major diseases that pose a threat to the health of residents in Guangxi. However, no systematic study has been performed to evaluate the time trends in the structure of cancer-related deaths and cancer mortality. In this study, we reveal sex, age and geography differences of cancers mortality between three death surveys (1971 to 1973, 1990 to 1992, and 2004 to 2005). The results show that the standardized mortality rate of cancer in Guangxi residents has risen from 43.3/100,000 to 84.2/100,000, the share of cancer deaths in all-cause deaths has increased from 13.3% to 20.7%, and cancer has become the second most common cause of death. The five major cancers, liver cancer, lung cancer, gastric cancer, nasopharyngeal cancer and colorectal cancer, account for 60% of all the cancer deaths. Cancers with growing mortality rates over the past 30 years include lung cancer, colorectal cancer, liver cancer and female breast cancer, of which lung cancer is associated with the sharpest rise in mortality, with a more than 600% rise in both men and women. Cancer death in Guangxi residents occurs mainly in the elderly population above 45 years of age, especially in people over the age of 65. The areas with the highest mortality rates for liver cancer and nasopharyngeal cancer, which feature regional high incidences, include Chongzuo and Wuzhou. Therefore, for major cancers such as liver cancer, lung cancer, gastric cancer, nasopharyngeal cancer and female breast cancer in Guangxi, we can select high-risk age groups as the target population for cancer prevention and control efforts in high-prevalence areas in a bid to achieve the ultimate goal of lowering cancer mortality in Guangxi.

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“…The smoking rate in Korean men was the highest in all Organization for Economic Co-operation and Development countries about 15 years ago and the rate did not significantly decline [4]. Although the cost-effectiveness of current national screening programs (breast, cervical, colon, and stomach cancers) was reported according to the principles of the national health screening program, the evidence for lung cancer screening has not been reported [5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Cost Utility Analysis of a Pilot Study for the Korean Lung Cancer Screening Project

et al. 2022

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The aim of this study was to evaluate the cost utility of a pilot study of Korean lung cancer screening project. Materials and MethodsWe constructed a Markov model consisting of 26 states based on the natural history of lung cancer according to the Surveillance, Epidemiology, and End Results summary stage (localized, regional, distant). In the base case, people aged 55-74 years were under consideration for annual screening. Costs and quality-adjusted life years were simulated to calculate the incremental cost utility ratio. Sensitivity analyses were performed on the uncertainty associated with screening target ages, stage distribution, cost, utility, mortality, screening duration, and discount rate. ResultsThe base case (US$25,383 per QALY gained) was cost-effective compared to the scenario of no screening and acceptable considering a willingness-to-pay threshold of US$27,000 per quality-adjusted life years gained. In terms of the target age of screening, the age between 60 and 74 years was the most cost-effective. Lung cancer screening was still cost-effective in the sensitivity analyses on the cost for treatment, utility, mortality, screening duration, and less than 5% discount rates, although the result was sensitive to a rise in positive rates or variation of stage distribution. ConclusionOur results showed the cost-effectiveness of annual low-dose computed tomography screening for lung cancer in high-risk populations.

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Cost-Effectiveness of Korea's National Cervical Cancer Screening Program

Cited by 7 publications

References 25 publications

Changing trends in the incidence (1999-2011) and mortality (1983-2013) of cervical cancer in the Republic of Korea

Changing trends in the incidence (1999-2011) and mortality (1983-2013) of cervical cancer in the Republic of Korea

Mortality of Major Cancers in Guangxi, China: Sex, Age and Geographical Differences from 1971 and 2005

Cost Utility Analysis of a Pilot Study for the Korean Lung Cancer Screening Project

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