2000
DOI: 10.7326/0003-4819-133-8-200010170-00007
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Cost-Effectiveness of Colonoscopy in Screening for Colorectal Cancer

Abstract: Colonoscopy represents a cost-effective means of screening for colorectal cancer because it reduces mortality at relatively low incremental costs. Low compliance rates render colonoscopy every 10 years the most cost-effective primary screening strategy for colorectal cancer.

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Cited by 439 publications
(240 citation statements)
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“…The continuing high mortality rates for patients with CRC, together with two large studies that demonstrate that FS fails to identify a substantial proportion of proximal lesions, 18,19 have led many specialists to regard reliance on FS or FOBT alone as screening tests would be as wrong as mammography of a single breast in screening for breast cancer. 12 A more detailed assessment of the costeffectiveness of alternative screening procedures 20 has led to somewhat surprising conclusions that may favor colonoscopy as a primary test. 21 However, cost is a major limitation to screening, and a more thorough assessment of the predictive value of findings derived from FS to ascertain proximal lesions is needed before accepting colonoscopy as a primary screening modality.…”
Section: Introductionmentioning
confidence: 99%
“…The continuing high mortality rates for patients with CRC, together with two large studies that demonstrate that FS fails to identify a substantial proportion of proximal lesions, 18,19 have led many specialists to regard reliance on FS or FOBT alone as screening tests would be as wrong as mammography of a single breast in screening for breast cancer. 12 A more detailed assessment of the costeffectiveness of alternative screening procedures 20 has led to somewhat surprising conclusions that may favor colonoscopy as a primary test. 21 However, cost is a major limitation to screening, and a more thorough assessment of the predictive value of findings derived from FS to ascertain proximal lesions is needed before accepting colonoscopy as a primary screening modality.…”
Section: Introductionmentioning
confidence: 99%
“…Na ocasião foram estudados e comparados, em relação a custo-efetividade, os exames de sangue oculto nas fezes, retossigmoidoscopia flexível, a combinação dos anteriores, e à colonoscopia (10,12,15,17) . Nos últimos anos, estudos comparativos têm enfatizado e indicado a colonoscopia como o exame inicial para o rastreamento do câncer colorretal devido sua melhor custo-efetividade em relação às outras opções de rastreamento, especialmente se considerados os níveis de adesão vislumbrados na Trabalho realizado na Fundação Rio-grandense Universitária de Gastroenterologia (FUGAST) e no Curso de Pós-graduação em Ciências Médicas da Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA).…”
Section: Introductionunclassified
“…Correspondência: Dr. Júlio Carlos Pereira-Lima -Rua Comendador Rheingantz, 910/801 -Bairro Bela Vista -90450-020 -Porto Alegre, RS. E-mail: jpereiralima@terra.com.br prática clínica -critério que influencia diretamente a relação custo-efetividade de qualquer exame com tal finalidade (15,17) . Desde então, a colonoscopia é tida como exame de eleição para rastreamento da população geral entre 50 e 60 anos de idade devido a sua elevada precisão diagnóstica e associado poder terapêutico.…”
Section: Introductionunclassified
“…Based on these and other findings, clinical guidelines have recommended colonoscopy as a screening modality for CRC [3,4]. Moreover, screening colonoscopy reduced CRC-associated mortality at a relatively low incremental cost [5]. Thus, colonoscopic screening can provide great benefit for patients at risk of CRC.…”
mentioning
confidence: 99%