Cost-effectiveness analysis of two kinds of bladder cancer urinary diversion: Studer versus Bricker

Mao, Weipu; Xie, Jinbo; Wu, Yuan; Wu, Zong-Lin; Wang, Keyi; Shi, Heng; Zhang, Hui; Peng, Bo; Geng, Jiang

doi:10.21037/tau.2020.03.46

Cited by 6 publications

(9 citation statements)

References 23 publications

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“…This methodology is consistent with prior works in this space, which allows comparison of this contemporary cohort and the historical literature ( 10 ). Charges have also been used for comparing treatment arms in more recent publications ( 33 - 35 ). The surgical castration cohort is a small sample size in relation to the chemical ADT group, but the proportion of surgical patients (5% of total) was actually slightly more than what has been reported for population surgical castration utilization ( 4 ).…”

Section: Discussionmentioning

confidence: 99%

Significant financial differences of chemical and surgical androgen deprivation in a contemporary cohort

Paul¹,

Garje²,

Kreder³

et al. 2022

Transl Androl Urol

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Background: Androgen deprivation therapy (ADT) remains a cornerstone of treatment for advanced prostate cancer. Few men elect for surgical castration via bilateral orchiectomy. We sought to compare the relative difference in financial charges between chemical and surgical ADT in men.Methods: Billing data was obtained for patients with metastatic prostate cancer receiving chemical ADT and who had bilateral orchiectomy from 2014-2019. Men had chosen intervention based on personal preference. We compared charges of ADT administration for chemical ADT and overall charges for bilateral orchiectomy. We determined the time chemical ADT patient charges surpassed those of surgical charges, as well as the net present value (NPV) of hypothetical savings for electing surgery over various ADT agents.Results: One hundred and thirty-seven patients receiving chemical ADT and 7 patients who had undergone bilateral orchiectomy were analyzed. Median and mean surgical charges were $13,000. By 38 weeks following treatment initiation, 50% of chemical ADT patients had surpassed surgical charges, with 95% at 2 years. The NPV in savings for a median patient varied between ADT agent and was highest at $167,000 for leuprolide. Conclusions:In less than a year, the median chemical ADT patient charges were greater than surgical castration. The NPV of electing surgery over ADT was the highest with leuprolide. Despite underutilization, surgical castration remains a medically appropriate and cost-effective option for permanent ADT.

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Section: Discussionmentioning

confidence: 99%

Significant financial differences of chemical and surgical androgen deprivation in a contemporary cohort

Paul¹,

Garje²,

Kreder³

et al. 2022

Transl Androl Urol

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“…For advanced BCa, RC and urinary diversion remain the gold standard (20). However, until now, it remained uncertain whether having a high BMI could result in a worse prognosis after cystectomy.…”

Section: Discussionmentioning

confidence: 99%

Extreme body mass index is associated with poor survival outcomes after radical cystectomy: a retrospective cohort study in a Chinese population

Huang¹,

Jin²,

Liu³

et al. 2021

Transl Androl Urol

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“…Questionnaire: QoL was assessed using the European Organization for Research and Treatment of Cancer QoL Questionnaire Core30 (EORTC QLQ‐C30) and the BCa specific instruments (EORTC QLQ‐BLM30). 19 , 20 , 21 There are two questions on a scale of one to seven score while the other questions are recorded on a scale of one to four score (1 = not at all; 2 = a little; 3 = quite a bit; 4 = very much). As recommended by the EORTC scoring manual, we linearly converted all variables to 0–100 points.…”

Section: Methodsmentioning

confidence: 99%

The effect of body mass index on quality of life in modified single stoma cutaneous ureterostomy or ileal conduit after radical cystectomy

Zhang,

Huang,

Lin

et al. 2023

Cancer Medicine

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ObjectiveTo explore the influence of postoperative body mass index (BMI) change on postoperative quality of life (QOL) in patients undergoing radical cystectomy (RC) plus modified single stoma cutaneous ureterostomy (MSSCU) or ileal conduit (IC).MethodsPatients were divided into two groups according to different BMI change patterns: patients experiencing an elevated postoperative BMI level, along with a clinically significant increase in their BMI (an increase of more than 10%) were categorized as Group 1, while patients experiencing a decrease postoperative BMI level, along with a clinically significant reduction in their BMI (a decrease of more than 5%) were categorized as Group 2. Spearman correlation analysis was used to examine the correlations between quality‐of‐life scores and postoperative clinical parameters.ResultsSpearman correlation analysis showed that postoperative BMI, late complications and catheter‐free state were significantly associated with postoperative global QoL and symptom scale in MSSCU and postoperative global QoL and physical scale in IC patients. Additionally, postoperative BMI, catheter‐free state and the use of adjuvant therapy were associated with bad performance in many scales of QoL like body image, future perspective, social scale, future perspective (MSSCU), and abdominal bloating (IC) (Table 2, p<0.05). Patients in Group 2 with significant weight loss had a better Global QoL, a lower rate of stomal stricture and a higher catheter‐free state compared with those in Group 1 in both IC and MSSCU patients. MSSCU patients in Group 2 could achieve a comparable Global QoL as to IC patients in Group 1.ConclusionControlling the substantial increase in body weight after surgery contributes to improving QoL, reducing the occurrence of stomal stricture, and ensuring a postoperative catheter‐free state in BCa patients undergoing MSSCU.

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Cost-effectiveness analysis of two kinds of bladder cancer urinary diversion: Studer versus Bricker

Cited by 6 publications

References 23 publications

Significant financial differences of chemical and surgical androgen deprivation in a contemporary cohort

Significant financial differences of chemical and surgical androgen deprivation in a contemporary cohort

Extreme body mass index is associated with poor survival outcomes after radical cystectomy: a retrospective cohort study in a Chinese population

The effect of body mass index on quality of life in modified single stoma cutaneous ureterostomy or ileal conduit after radical cystectomy

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