Cost-effectiveness analysis of phenotypic-guided vs. guidelines-guided bronchodilator therapy in viral bronchiolitis

Abstract

Objectives. Although recent evidence suggests that management of viral bronchiolitis requires something other than guidelinesguided therapy, there is a lack of evidence supporting the economic benefits of phenotypic-guided bronchodilator therapy for treating this disease. The aim of the present study was to compare the cost-effectiveness of phenotypic-guided versus guidelinesguided bronchodilator therapy in infants with viral bronchiolitis. Methods: A decision-analysis model was developed in order to compare the cost-effectiveness of phenotypic-guided versus guidelines-guided bronchodilator therapy in infants with viral