Cost-effectiveness analysis comparing continuation of art with conversion to iui in patients with low follicle numbers

Yu, Bo; Segars, James H.; Armstrong, Anne

doi:10.1016/j.fertnstert.2011.07.017

Cited by 2 publications

(2 citation statements)

References 21 publications

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“…Our analysis did not directly account for potential changes in the cost of IVF over the five year period between OC and pregnancy attempts at age 40 years due to potential inflation/deflation or changes in technology or other factors, however sensitivity analyses varied the cost of OC and IVF cycles to evaluate potential effects on our findings were the cost of IVF to change. Using similar methods to sample regionally diverse clinics for IVF pricing, we found that the median cost of an ART cycle including medications was relatively stable from 2011 to 2014 and were consistent with those reported by ASRM and RESOLVE (39). Of note, the majority of clinics include the cost of assisted hatching and ICSI in their IVF pricing.…”

Section: Discussionsupporting

confidence: 79%

Baby budgeting: oocyte cryopreservation in women delaying reproduction can reduce cost per live birth

Devine

Mumford

Goldman

et al. 2015

Fertility and Sterility

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Objective To determine whether oocyte cryopreservation (OC) for deferred reproduction is cost-effective per live birth using a model constructed from observed clinical practice. Design Decision-tree mathematical model with sensitivity analyses. Setting Not applicable. Patients A simulated cohort of women wishing to delay childbearing until age 40 years. Interventions Not applicable. Main Outcome Measure Cost per live birth. Results Our primary model predicted that OC at age 35 years by women planning to defer pregnancy attempts until age 40 would decrease cost per live birth to $39,946 (and increase odds of live birth to 62% by the end of the model),indicating OC to be a cost-effective strategy relative to forgoing OC, which was associated with a predicted cost per live birth of $55,060 (and 42% chance of live birth). If fresh autologous ART was added at age 40 prior to thawing oocytes, 74% obtained a live birth, though at an increased cost of $61,887. Separate sensitivity analyses demonstrated that OC remained cost-effective so long as patients underwent OC prior to age 38, more than 49% of those not obtaining a spontaneously conceived live birth returned to thaw oocytes, and likelihood of obtaining a spontaneously conceived live birth after six months’ attempts at age 40 was less than 35%. Conclusions In women who plan to delay childbearing until age 40, oocyte cryopreservation before 38 years of age reduces the cost to obtain a live birth.

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Section: Discussionsupporting

confidence: 79%

Baby budgeting: oocyte cryopreservation in women delaying reproduction can reduce cost per live birth

Devine

Mumford

Goldman

et al. 2015

Fertility and Sterility

View full text Add to dashboard Cite

show abstract

“…2 The researchers used a decision-tree model based on data obtained from a search of PubMed. 2 The researchers used a decision-tree model based on data obtained from a search of PubMed.…”

Section: Better To Continue With Artmentioning

confidence: 99%

Bearing the burden of fertility treatment choices

2011

Pharmacoecon. Outcomes News

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Cost-effectiveness analysis comparing continuation of art with conversion to iui in patients with low follicle numbers

Cited by 2 publications

References 21 publications

Baby budgeting: oocyte cryopreservation in women delaying reproduction can reduce cost per live birth

Baby budgeting: oocyte cryopreservation in women delaying reproduction can reduce cost per live birth

Bearing the burden of fertility treatment choices

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