Cost-Effective, Microstrip Antenna Driven Ring Resonator Microwave Biosensor for Biospecific Detection of Glucose

Camli, Berk; Kusakci, Emre; Lafci, Berkan; Salman, Seyhan; Torun, Hamdi

doi:10.1109/jstqe.2017.2659226

Cited by 53 publications

(44 citation statements)

References 30 publications

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“…3, which shows our proposed glucose sensor is with very high sensitivity of 108.4 MHz/mg/ml compared to 0.107 MHz/mg/ml [19], very high linear correlation 0.9979 compared to 0.79 [19]. Sample requirement in this proposed work is only 20 µl compared to 90 µl [19] in the literature. The device reported in literature [19] needs a laser cutter to make the cavity to confine the AUT, whereas the proposed CPW glucose sensor is easy to design and is fabricated in-house.…”

Section: Discussionmentioning

confidence: 81%

“…A comparison of our proposed CPW planar glucose sensor with the ring resonator based glucose sensor reported by Camli et al [19] on the basis of various aspects, such as performance, design, fabrication, and measurements as listed in Tab. 3, which shows our proposed glucose sensor is with very high sensitivity of 108.4 MHz/mg/ml compared to 0.107 MHz/mg/ml [19], very high linear correlation 0.9979 compared to 0.79 [19]. Sample requirement in this proposed work is only 20 µl compared to 90 µl [19] in the literature.…”

Section: Discussionmentioning

confidence: 99%

“…Sample requirement in this proposed work is only 20 µl compared to 90 µl [19] in the literature. The device reported in literature [19] needs a laser cutter to make the cavity to confine the AUT, whereas the proposed CPW glucose sensor is easy to design and is fabricated in-house.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Coplanar Waveguide Microwave Sensor for Label-Free Real-Time Glucose Detection

Sameer¹,

Agarwal²

2019

RADIOENGINEERING

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In this work, a real-time label-free microwave diagnostic approach using Co-Planar Waveguide (CPW) design has been demonstrated for glucose detection. This mechanism has tremendous potential for the biomedical applications. Here, glucose biosensor is implemented with 50Ω CPW transmission line, where the centre localized 3mm diameter of CPW transmission line has been used for the sensing. Glucose sensor is implemented utilizing low cost multilayer PCB and polymer Poly-Di-Methyl-Siloxane(PDMS) fabrication technology. CPW transmission line is fabricated on FR4 microwave laminate board. To confine the Analyte Under Test (AUT) on the sensing area, PDMS polymer cavity is configured in the centre of CPW transmission line. The electromagnetic interaction with the varying dielectric constant of Glucose:DI water solution results shift in S 11 parameter, which is closely observed to use as the source of sensing. CPW based glucose sensor is experimentally measured for S 11 parameter using VNA, with varying glucose concentration range from 0 mg/ml (only DI water) to 4 mg/ml with the interval of 1 mg/ml. The measured results showed good sensitivity of 108.4 MHz/mg/ml and high accuracy with good linear regression coefficient of 0.9979.

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Section: Discussionmentioning

confidence: 81%

Section: Discussionmentioning

confidence: 99%

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Coplanar Waveguide Microwave Sensor for Label-Free Real-Time Glucose Detection

Sameer¹,

Agarwal²

2019

RADIOENGINEERING

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“…For a biosensor application, biospecificity is possible with the functionalization of the resonator surface with a biospecific agent. In this scenario, any biochemical binding or reaction changes the electrical permittivity of the medium to enable sensing [5].…”

Section: Introductionmentioning

confidence: 99%

Reference-Incorporating Microwave Resonator-Based Sensors for Biological Sensing Applications

Camli

Torun

Dündar

et al. 2017

Proceedings of Eurosensors 2017, Paris, France, 3–6 September 2017

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Use of microwave resonator-based sensors is a relatively new approach for the detection of biological reagents. Sensing mechanism is based on the tracking of the resonant frequency on electromagnetic resonator. Resonant frequency depends on structure geometry and material but is also affected by secondary changes in environment. Addition of a reference resonator to suppress these effects is proposed in this work. Identical sensor structures designed at 2 GHz, fabricated using low-cost processes are used in experiments to demonstrate the use of a resonator pair for sensing of glucose in solutions, yielding a sensitivity of 34.72 MHz/ (mg/mL).

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“…When the designed split ring resonator (SRR) is covered by different liquids, the resonant frequency shifts due to the change of surrounding media permittivity. Therefore, such liquid solution tunable metasurface can be used to detect the electromagnetic properties of the liquids[157].Instead of water, liquid solutions like ethanol and petrol[158], glucose[159] are also used to realize the tuning of optical response in microwave region.Studies of liquid solution tunable metasurfaces applied to fluidic bio-chemicalsensors are also demonstrated using liquids with different concentrations[160][161][162].The fluids are positioned close to the gap of the metamolecules, where a strong electric field is established. Therefore, a small change of the liquid concentration will lead to the resonance shift of the metasurfaces.…”

mentioning

confidence: 99%

Meta-fluidic-surfaces for electromagnetic wave manipulations

Yan¹

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Cost-Effective, Microstrip Antenna Driven Ring Resonator Microwave Biosensor for Biospecific Detection of Glucose

Cited by 53 publications

References 30 publications

Coplanar Waveguide Microwave Sensor for Label-Free Real-Time Glucose Detection

Coplanar Waveguide Microwave Sensor for Label-Free Real-Time Glucose Detection

Reference-Incorporating Microwave Resonator-Based Sensors for Biological Sensing Applications

Meta-fluidic-surfaces for electromagnetic wave manipulations

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