Cost Burden of Chronic Pain Patients in a Large Integrated Delivery System in the United States

Park, Peter W.; Dryer, Richard D.; Hegeman-Dingle, Rozelle; Mardekian, Jack; Zlateva, Gergana; Wolff, G; Lamerato, Lois

doi:10.1111/papr.12357

Cited by 46 publications

(40 citation statements)

References 29 publications

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“…The majority of studies were from USA ( n = 28) , followed by UK ( n = 4 studies) , Spain ( n = 3 studies) and Canada ( n = 3 studies) , with single studies from Norway , Denmark , Australia and India . There were no studies that compared data from multiple countries.…”

Section: Resultsmentioning

confidence: 99%

What proportion of patients with chronic noncancer pain are prescribed an opioid medicine? Systematic review and meta‐regression of observational studies

et al. 2020

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Mathieson S, ). What proportion of patients with chronic noncancer pain are prescribed an opioid medicine? Systematic review and meta-regression of observational studies (Review). J Intern Med 2020; 287: 458-474.Guidelines now discourage opioid analgesics for chronic noncancer pain because the benefits frequently do not outweigh the harms. We aimed to determine the proportion of patients with chronic noncancer pain who are prescribed an opioid, the types prescribed and factors associated with prescribing. Database searches were conducted from inception to 29 October 2018 without language restrictions. We included observational studies of adults with chronic noncancer pain measuring opioid prescribing. Opioids were categorized as weak (e.g. codeine) or strong (e.g. oxycodone). Study quality was assessed using a risk of bias tool designed for observational studies measuring prevalence. Individual study results were pooled using a random-effects model. Meta-regression investigated study-level factors associated with prescribing (e.g. sampling year, geographic region as per World Health Organization). The overall evidence quality was assessed using Grading of Recommendations Assessment, Development and Evaluation criteria. Of the 42 studies (5,059,098 participants) identified, the majority (n = 28) were from the United States of America. Eleven studies were at low risk of bias. The pooled estimate of the proportion of patients with chronic noncancer pain prescribed opioids was 30.7% (95% CI 28.7% to 32.7%, n = 42 studies, moderate-quality evidence). Strong opioids were more frequently prescribed than weak (18.4% (95% CI 16.0-21.0%, n = 15 studies, low-quality evidence), versus 8.5% (95% CI 7.2-9.9%, n = 15 studies, low-quality evidence)). Meta-regression determined that opioid prescribing was associated with year of sampling (more prescribing in recent years) (P = 0.014) and not geographic region (P = 0.056). Opioid prescribing for patients with chronic noncancer pain is common and has increased over time.

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Section: Resultsmentioning

confidence: 99%

What proportion of patients with chronic noncancer pain are prescribed an opioid medicine? Systematic review and meta‐regression of observational studies

et al. 2020

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“…3,24,25 When these comorbidities exist, healthcare costs are considerable higher. 27,28 Besides psychosocial factors regarding dealing with pain (such as fear of movement, pain catastrophizing, low pain self-efficacy, and passive pain coping), depression, anxiety and somatization, influence the prognosis of people with musculoskeletal pain. 3,18,36 Positively influencing these psychosocial factors optimizes recovery.…”

Section: Introductionmentioning

confidence: 99%

Preferred Self-Administered Questionnaires to Assess Depression, Anxiety and Somatization in People With Musculoskeletal Pain – A Modified Delphi Study

Bijker

Sleijser-Koehorst

Coppieters

et al. 2020

The Journal of Pain

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Depression, anxiety, and somatization influence the recovery of people with musculoskeletal pain. A Delphi study was conducted to reach consensus on the most appropriate self-administered questionnaires to assess these psychosocial factors in people at risk of developing persistent musculoskeletal pain. A multidisciplinary panel of international experts was identified via PubReMiner. The experts (N = 22) suggested 24 questionnaires in Round 1. In Round 2, experts rated the questionnaires on suitability, considering clinimetrics, content, feasibility, personal experiences, and expertise. The highest ranked questionnaires were retained for Round 3, in which the experts made a final assessment of the suitability of the questionnaires. Sensitivity analyses were performed to assess the impact of 1) not all experts having participated in each round, and 2) experts having been involved in relevant questionnaire development. Consensus (ie, ≥75% agreement) was reached for the following questionnaires.Perspective: This study generated a short list of preferred questionnaires to assess depression, anxiety, and somatization in people with musculoskeletal pain. Broad implementation of these questionnaires by clinicians and researchers will facilitate easier comparison and pooling of baseline and outcome data. Some of the recommended questionnaires still require validation in this population.

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“…An interesting study from the Henry Ford Health System looked at the cost burden of patients with chronic pain by creating a de-identified, integrated administrative database in which both clinical information from the electronic medical record (EMR) and resource utilization data was searchable (16). This study reported on the rates of outpatient visits, imaging, opioid prescriptions, and associated costs, including global costs.…”

Section: Discussionmentioning

confidence: 99%

Challenges in the Analysis of Outcomes for Surgical Compared to Radiotherapy Treatment of Prostate Cancer

Glaser

Kalash

Bongiorni

et al. 2018

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Cost Burden of Chronic Pain Patients in a Large Integrated Delivery System in the United States

Cited by 46 publications

References 29 publications

What proportion of patients with chronic noncancer pain are prescribed an opioid medicine? Systematic review and meta‐regression of observational studies

What proportion of patients with chronic noncancer pain are prescribed an opioid medicine? Systematic review and meta‐regression of observational studies

Preferred Self-Administered Questionnaires to Assess Depression, Anxiety and Somatization in People With Musculoskeletal Pain – A Modified Delphi Study

Challenges in the Analysis of Outcomes for Surgical Compared to Radiotherapy Treatment of Prostate Cancer

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