COST B2: why and wherefore

Britton, K. E.; Sokole, Ellinor Busemann

doi:10.1007/bf00596384

Cited by 10 publications

(2 citation statements)

References 8 publications

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“…Quality control (QC) of clinical equipment, such as scintillation cameras and SPECT systems, is common and necessary procedures to ensure best quality of acquired images in nuclear medicine. However, testing of clinical software and validation of standard procedures should be considered equally important for studies where quantitative image analysis is performed and hence be included as a part of the quality assurance (QA) (Britton & Sokole, ).…”

Section: Introductionmentioning

confidence: 99%

The accuracy of quantitative parameters in ^99mTc‐MAG3 dynamic renography: a national audit based on virtual image data

Brolin

Edenbrandt

Granerus

et al. 2014

Clin Physio Funct Imaging

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Assessment of image analysis methods and computer software used in (99m) Tc-MAG3 dynamic renography is important to ensure reliable study results and ultimately the best possible care for patients. In this work, we present a national multicentre study of the quantification accuracy in (99m) Tc-MAG3 renography, utilizing virtual dynamic scintigraphic data obtained by Monte Carlo-simulated scintillation camera imaging of digital phantoms with time-varying activity distributions. Three digital phantom studies were distributed to the participating departments, and quantitative evaluation was performed with standard clinical software according to local routines. The differential renal function (DRF) and time to maximum renal activity (Tmax ) were reported by 21 of the 28 Swedish departments performing (99m) Tc-MAG3 studies as of 2012. The reported DRF estimates showed a significantly lower precision for the phantom with impaired renal uptake than for the phantom with normal uptake. The Tmax estimates showed a similar trend, but the difference was only significant for the right kidney. There was a significant bias in the measured DRF for all phantoms caused by different positions of the left and right kidney in the anterior-posterior direction. In conclusion, this study shows that virtual scintigraphic studies are applicable for quality assurance and that there is a considerable uncertainty associated with standard quantitative parameters in dynamic (99m) Tc-MAG3 renography, especially for patients with impaired renal function.

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Section: Introductionmentioning

confidence: 99%

The accuracy of quantitative parameters in ^99mTc‐MAG3 dynamic renography: a national audit based on virtual image data

Brolin

Edenbrandt

Granerus

et al. 2014

Clin Physio Funct Imaging

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show abstract

“…Therefore, the phantom results obtained will give only an impression of repeatability and variability, but they do not necessarily reflect the accuracy of measurements in patients. Therefore, in addition to the phantom measurements, a set of reference patient studies should also be included in a validation of the technique [ 40 ]. Moreover, the results should be validated in each separate centre and monitored for reproducibility and consistency.…”

Section: Discussionmentioning

confidence: 99%

Variations in 123I-metaiodobenzylguanidine (MIBG) late heart mediastinal ratios in chronic heart failure: a need for standardisation and validation

Verberne

Habraken

Eck-Smit

et al. 2007

Eur J Nucl Med Mol Imaging

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COST B2: the quality assurance of nuclear medicine software

Britton

Vauramo²

1993

Eur J Nucl Med

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COST B2: why and wherefore

Cited by 10 publications

References 8 publications

The accuracy of quantitative parameters in ^99mTc‐MAG3 dynamic renography: a national audit based on virtual image data

The accuracy of quantitative parameters in ^99mTc‐MAG3 dynamic renography: a national audit based on virtual image data

Variations in 123I-metaiodobenzylguanidine (MIBG) late heart mediastinal ratios in chronic heart failure: a need for standardisation and validation

COST B2: the quality assurance of nuclear medicine software

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COST B2: why and wherefore

Cited by 10 publications

References 8 publications

The accuracy of quantitative parameters in 99mTc‐MAG3 dynamic renography: a national audit based on virtual image data

The accuracy of quantitative parameters in 99mTc‐MAG3 dynamic renography: a national audit based on virtual image data

Variations in 123I-metaiodobenzylguanidine (MIBG) late heart mediastinal ratios in chronic heart failure: a need for standardisation and validation

COST B2: the quality assurance of nuclear medicine software

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The accuracy of quantitative parameters in ^99mTc‐MAG3 dynamic renography: a national audit based on virtual image data

The accuracy of quantitative parameters in ^99mTc‐MAG3 dynamic renography: a national audit based on virtual image data