“…38,[110][111][112] Furthermore, NIRS can eliminate the need for a specialized intensive nursing care and, thus can reduce the cost. 113 There have been 3 comparative studies evaluating the combination of NIRS and clinical monitoring against clinical monitoring alone. 33,34,39 All 3 studies reported high flap salvage rates (94%, 100%, and 100%, respectively), but only 2 trials showed statistical significance.…”