Cosmic radiation monitoring at low-Earth orbit by means of thermoluminescence and plastic nuclear track detectors

Ambrožová, Iva; Brabcová, Kateřina Pachnerová; Kubančák, Jan; Šlegl, Jakub; Tolochek, Raisa; Ivanova, Оlga А.; Shurshakov, Vyacheslav

doi:10.1016/j.radmeas.2016.12.004

Cited by 9 publications

(3 citation statements)

References 25 publications

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“…In addition, other space environmental factors appear to be involved in the reduction of the spleen mass. Because the altitude of the Bion-M1 satellite’s on-orbit flight (at 550 km) was higher than that of conventional manned spaceflight (at about 400 km) such as the ISS and Space Shuttle, the radiation dose during flight appears to also be different 32,38 (see also https://genelab-data.ndc.nasa.gov/). Thus, high dose radiation may contribute to the reduction of spleen mass reported in post-flight observations.…”

Section: Discussionmentioning

confidence: 99%

Down-regulation of GATA1-dependent erythrocyte-related genes in the spleens of mice exposed to a space travel

Horie¹,

Sasanuma²,

Kudo³

et al. 2019

Sci Rep

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Secondary lymphoid organs are critical for regulating acquired immune responses. The aim of this study was to characterize the impact of spaceflight on secondary lymphoid organs at the molecular level. We analysed the spleens and lymph nodes from mice flown aboard the International Space Station (ISS) in orbit for 35 days, as part of a Japan Aerospace Exploration Agency mission. During flight, half of the mice were exposed to 1 g by centrifuging in the ISS, to provide information regarding the effect of microgravity and 1 g exposure during spaceflight. Whole-transcript cDNA sequencing (RNA-Seq) analysis of the spleen suggested that erythrocyte-related genes regulated by the transcription factor GATA1 were significantly down-regulated in ISS-flown vs. ground control mice. GATA1 and Tal1 (regulators of erythropoiesis) mRNA expression was consistently reduced by approximately half. These reductions were not completely alleviated by 1 g exposure in the ISS, suggesting that the combined effect of space environments aside from microgravity could down-regulate gene expression in the spleen. Additionally, plasma immunoglobulin concentrations were slightly altered in ISS-flown mice. Overall, our data suggest that spaceflight might disturb the homeostatic gene expression of the spleen through a combination of microgravity and other environmental changes.

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Section: Discussionmentioning

confidence: 99%

Down-regulation of GATA1-dependent erythrocyte-related genes in the spleens of mice exposed to a space travel

Horie¹,

Sasanuma²,

Kudo³

et al. 2019

Sci Rep

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“…5A). In the case of BION (47,48) (Fig. 5B) and ISS, both passive (thermoluminescent dosimeters, TLDs or plastic nuclear track detectors, PNTDs) and active (solid state, tissue equivalent proportional counters) were used.…”

Section: Space Radiation Dosimetrymentioning

confidence: 99%

NASA GeneLab Project: Bridging Space Radiation Omics with Ground Studies

et al. 2018

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Accurate assessment of risks of long-term space missions is critical for human space exploration. It is essential to have a detailed understanding of the biological effects on humans living and working in deep space. Ionizing radiation from galactic cosmic rays (GCR) is a major health risk factor for astronauts on extended missions outside the protective effects of the Earth's magnetic field. Currently, there are gaps in our knowledge of the health risks associated with chronic low-dose, low-dose-rate ionizing radiation, specifically ions associated with high (H) atomic number (Z) and energy (E). The NASA GeneLab project ( https://genelab.nasa.gov/ ) aims to provide a detailed library of omics datasets associated with biological samples exposed to HZE. The GeneLab Data System (GLDS) includes datasets from both spaceflight and ground-based studies, a majority of which involve exposure to ionizing radiation. In addition to detailed information on radiation exposure for ground-based studies, GeneLab is adding detailed, curated dosimetry information for spaceflight experiments. GeneLab is the first comprehensive omics database for space-related research from which an investigator can generate hypotheses to direct future experiments, utilizing both ground and space biological radiation data. The GLDS is continually expanding as omics-related data are generated by the space life sciences community. Here we provide a brief summary of the space radiation-related data available at GeneLab.

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“…Plastic dosimeters represent an important role in radiation applications [1][2][3][4][5]. They have been used in a variety of applications, such as portal monitors [6], solar radiation [7], radiation attenuation [8], cosmic radiation [9], UV radiation [10], thermal radiation [11] and gamma radiation [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Plastic bottle caps as radiation detectors for high gamma radiation doses

Oliveira¹,

Nascimento²,

Antonio³

et al. 2022

Braz. J. Rad. Sci.

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Dosimetric evaluation is indicated for material characterization seeking to identify possible applications; still, proper preprocessing techniques are critical features of this process. This work aimed to determine the linearity response of plastic samples irradiated with gamma rays using the Fourier Transform Infrared (FTIR) measurements. The plastic samples were analyzed using Derivatives and Principal Component Analysis (PCA) methods. They applied linear and Principal Component Regression (PCR) methods to obtain linearity. The methods obtained good results for linearity and also showed the evolution of each technique. In conclusion, the results indicate that the applied methods can be useful in radiation physics and for plastic samples as interesting potential radiation detectors.

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Cosmic radiation monitoring at low-Earth orbit by means of thermoluminescence and plastic nuclear track detectors

Cited by 9 publications

References 25 publications

Down-regulation of GATA1-dependent erythrocyte-related genes in the spleens of mice exposed to a space travel

Down-regulation of GATA1-dependent erythrocyte-related genes in the spleens of mice exposed to a space travel

NASA GeneLab Project: Bridging Space Radiation Omics with Ground Studies

Plastic bottle caps as radiation detectors for high gamma radiation doses

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