Cosmetovigilance survey: Are cosmetics considered safe by consumers?

Giovanni, Carmen Di; Arcoraci, Vincenzo; Gambardella, Loredana; Sautebin, Lidia

doi:10.1016/j.phrs.2005.08.003

Cited by 54 publications

(50 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Despite this, cosmetics and bodycare products represent potentially the commonest exposure scenario to chemicals in individuals and the population as a whole. Recent reports of cosmetics safety in use show a surprisingly high percentage of adverse reactions to products, with 26.5% of women and 17.4% of men reporting an adverse event/reaction to cosmetic use (Di Giovanni et al, 2006). Of the reactions reported, 95.9% involved the skin and 4.1% were systemic reactions, and of these reports of systemic reactions, headache was the most common (40.3%) followed by nausea (24.2%).…”

Section: Regulatory Status Of Parabensmentioning

confidence: 99%

Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks

Darbre

Harvey

2008

J of Applied Toxicology

584

375

View full text Add to dashboard Cite

This toxicology update reviews research over the past four years since publication in 2004 of the ¼rst measurement of intact esters of p-hydroxybenzoic acid (parabens) in human breast cancer tissues, and the suggestion that their presence in the human body might originate from topical application of bodycare cosmetics. The presence of intact paraben esters in human body tissues has now been con¼rmed by independent measurements in human urine, and the ability of parabens to penetrate human skin intact without breakdown by esterases and to be absorbed systemically has been demonstrated through studies not only in vitro but also in vivo using healthy human subjects. Using a wide variety of assay systems in vitro and in vivo, the oestrogen agonist properties of parabens together with their common metabolite ( p-hydroxybenzoic acid) have been extensively documented, and, in addition, the parabens have now also been shown to possess androgen antagonist activity, to act as inhibitors of sulfotransferase enzymes and to possess genotoxic activity. With the continued use of parabens in the majority of bodycare cosmetics, there is a need to carry out detailed evaluation of the potential for parabens, together with other oestrogenic and genotoxic co-formulants of bodycare cosmetics, to increase female breast cancer incidence, to interfere with male reproductive functions and to in½uence development of malignant melanoma which has also recently been shown to be in½uenced by oestrogenic stimulation.

show abstract

Section: Regulatory Status Of Parabensmentioning

confidence: 99%

Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks

Darbre

Harvey

2008

J of Applied Toxicology

584

375

View full text Add to dashboard Cite

show abstract

“…7 (In an Italian poll published in 2006, more than 50% of the people who experienced an adverse reaction to a cosmetic did not seek medical advice.) 8 A recent survey of a non-selected population in the United Kingdom revealed that 23% of women and 13.8% of men experience some sort of adverse reaction to a personal care product over the course of a year, with an increase in overall rates of 51.4% and 38.2% over a lifetime. 9 Although they are quite common, only a minority of adverse reactions to cosmetics in the general population have been shown to be allergic in origin [10][11][12] highlighting that despite the widespread use of personal care products, the rates of allergic reactions to their ingredients are relatively low.…”

Section: Adverse Reactions To Cosmeticsmentioning

confidence: 99%

Patterns of Cosmetic Contact Allergy

Castanedo-Tardan

Zug

2009

Dermatologic Clinics

View full text Add to dashboard Cite

“…Despite social perception of their safety and tolerability, during recent decades there is evidence for harmful effects of these products [5–7]. Globally, reported numbers of adverse events are so far very low [8]. This underestimation can be mainly attributed to self-diagnosis, self-use (medication), and the absence of medical consultation, particularly by users may not recognize or give attention to mild and moderate harmful events [8].…”

Section: Introductionmentioning

confidence: 99%

“…Globally, reported numbers of adverse events are so far very low [8]. This underestimation can be mainly attributed to self-diagnosis, self-use (medication), and the absence of medical consultation, particularly by users may not recognize or give attention to mild and moderate harmful events [8]. In addition, underestimation of such harmful effects may be because of the absence of formal and reliable monitoring systems (‘cosmetovigilance’) being in place [9].…”

Section: Introductionmentioning

confidence: 99%

Cosmetics Use-Related Adverse Events and Determinants Among Jigjiga Town Residents, Eastern Ethiopia

Bilal

Tilahun

Osman

et al. 2016

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

IntroductionNon-medicated cosmetics use is very common among the Ethiopian population. However, little is known about these products’ related adverse events. The aim of this study was to assess the prevalence and determinants of cosmetics-related adverse events among Jigjiga Town residents, Eastern Ethiopia.MethodsA community-based cross-sectional study design was conducted in May and June 2014. Semi-structured interviews were used to collect cosmetics use pattern and related adverse events. For assessing determinants, logistic regression was used and statistical significance was set at p < 0.05.ResultsOverall, 600 participants were approached with a 93% response rate. Ninety-three percent (n = 521) of them reported the use of cosmetics at least once within 2 weeks prior to this study, and of these, 229 (44%) used traditional herbal cosmetics along with modern cosmetics. A total of 342 (61%) reported experiencing adverse events of which the most common reported were: allergic reactions, 149 (36%); the appearance of acne, 66 (16%); and hirsutism, 52 (12.5%). The occurrence of cosmetics-related adverse events were significantly associated with the number of cosmetics used per day, the frequency of use, mixing of different types of cosmetics together, and mixing of cosmetics with water or saliva.ConclusionA higher proportion of cosmetic users reported experiencing at least one adverse event. The number of cosmetic products and frequency of use were important predictors for experiencing adverse events. This implies the need to consider safety concerns related to cosmetic use. Approaches to address such issues may include awareness creation programs and promoting the concept of cosmetovigilance among cosmetic sellers, users, and other stakeholders.

show abstract

Cosmetovigilance survey: Are cosmetics considered safe by consumers?

Cited by 54 publications

References 20 publications

Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks

Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks

Patterns of Cosmetic Contact Allergy

Cosmetics Use-Related Adverse Events and Determinants Among Jigjiga Town Residents, Eastern Ethiopia

Contact Info

Product

Resources

About