Abstract:SummaryBackgroundSystemic inflammatory response syndrome (SIRS) changes cortisol dynamics and indicates dissociation between the adrenal cortex and the hypothalamo-pituitary unit. The aim of this study was to assess the cortisol response after stimulation with ACTH1-24 in patients with SIRS at admission to the Respiratory Intensive Care Unit (RICU) and seven days later.MethodsFifty-four subjects were included in the study, and SIRS was defined according to the Consensus Conference criteria from 1992. Severity … Show more
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