Cortisol awakening rise in middle-aged women in relation to psychological stress

O’Connor, Daryl B.; Hendrickx, H.; Dadd, Tony; Elliman, Toby D; Willis, Thomas A.; Talbot, D; Mayes, Andrew E.; Thethi, Karen; Powell, Jonathan R.; Dye, Louise

doi:10.1016/j.psyneuen.2009.05.002

Cited by 81 publications

(60 citation statements)

References 51 publications

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“…A number of previous studies that examined associations of perceived stress, job strain, and fatigue/burnout with awakening cortisol response indirectly support the current results 34,39,40,[41][42][43] . A meta-analyses of studies on the relationship between psychosocial factors and waking cortisol found that waking cortisol is positively associated with job and general life stress but was negatively associated with fatigue, burnout and exhaustion 42) . In a study of school teachers where saliva samples were collected at 15, 30, and 60 min following awakening, the study found that those scoring high on burnout had lower overall cortisol secretion 44) .…”

Section: Discussionsupporting

confidence: 83%

“…In a study of school teachers where saliva samples were collected at 15, 30, and 60 min following awakening, the study found that those scoring high on burnout had lower overall cortisol secretion 44) . Studies of middle-aged women 42) and hospital nurses 40) found perceived stress level was negatively correlated with waking salivary cortisol concentration where those in the high stress group secreted lower levels of waking cortisol compared to those in the low stress group. A longitudinal study of retail industry workers 39) found that salivary cortisol was inversely associated with job strain; higher concentrations were observed among subjects with low job strain compared to those experiencing high job strain.…”

Section: Discussionmentioning

confidence: 99%

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Associations of Long-term Shift Work with Waking Salivary Cortisol Concentration and Patterns among Police Officers

et al. 2012

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The objective of this study was to evaluate whether long-term shift work is associated with both the total hormonal secretion after awakening and the pattern of the cortisol levels during the first hour following awakening, among 65 randomly selected police officers who represent a high stress occupation. Dominant shift (Day, Afternoon, or Midnight) was ascertained using daily payroll records of each participant's work activities during the 6-8 yrs prior to saliva sampling. Four salivary samples were collected at 15 min intervals upon first awakening. After accounting for potential confounders, salivary cortisol concentrations averaged across all four time points and total area under the curve differed significantly across shift with midnight shift workers showing suppressed awakening cortisol response relative to the afternoon and day shift. The percent of hours worked on midnight shift was inversely correlated with total awakening cortisol output. In contrast, the pattern of cortisol secretion during the first hour following waking appeared not to be affected as no significant interaction effect was found between time since awakening and shift work. The results show that long-term midnight shift work is associated with decreased absolute mean level and total volume of cortisol released over the waking period.

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Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Associations of Long-term Shift Work with Waking Salivary Cortisol Concentration and Patterns among Police Officers

et al. 2012

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“…However, a number of studies have shown that high levels of trait stress are associated with lower cortisol levels in the morning (e.g. O'Connor et al, 2009;Thorn et al, 2006). Therefore, the literature shows a number of different effects on the CAR relating the various measures of stress.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, the methods used in the current study have been shown to be appropriate for healthy participants, for whom there should be a rise in cortisol levels in the morning (e.g. O'Connor et al, 2009;Thorn et al, 2006). Moreover, we included a number of methodological features to the participant study briefings that are likely to have substantially reduced protocol adherence problems (e.g., explaining that the experimenters could identify protocol non-adherence in the samples, ensuring that participants kept diaries and received reminders).…”

Section: Discussionmentioning

confidence: 99%

Exploring day-to-day dynamics of daily stressor appraisals, physical symptoms and the cortisol awakening response

Gartland

O’Connor

Lawton

et al. 2014

Psychoneuroendocrinology

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Stress is associated with the secretion of cortisol throughout the day, but less is known about the dynamic effects of stress on the cortisol awakening response (CAR). More widely, knowledge of the causal factors and functions of the CAR are also not fully understood. This study explored: (1) the effects of daily stressors on the next day CAR and; (2) the effects of the CAR on same day physical and affective outcomes. Sixty-four participants completed a daily diary, reporting on the occurrence of daily stressors and stress appraisals, physical symptoms, and affect. Cortisol was measured at 0, 15, 30, and 45 minutes after awakening to provide measures of the CAR on 3 consecutive work days. Stress appraisal was found to negatively predict the CAR, such that where stressors were appraised as more stressful (where perceived demands exceeded resources), the CAR increased less the following morning. Furthermore, the CAR significantly predicted same-day physical symptoms such that a lower CAR was associated with more physical symptoms. This study provides evidence for a pathway through which daily stressors may influence physical wellbeing, and highlights the importance of appraisals for future stress-based cortisol research.

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“…In support of this idea, women with FMS have lower urinary [10] and salivary cortisol levels [20] than healthy controls and less diurnal variability in comparison to individuals with rheumatoid arthritis (RA) [24]. In addition, core features of FMS, such as fatigue, pain, and psychological stress, have been associated with lower morning cortisol levels and blunted diurnal slopes [46][47][48]. Previous studies have suggested that HPA axis is perturbed in FMS [24,49,50] and hyperreactive response to different stimuli of ACTH and GH was detected, whereas in the cortisol response, a decrease observed [23,49].…”

Section: Cortisol Abnormalities In Fmsmentioning

confidence: 99%

Is Fibromyalgia a Syndrome of Hormonal Imbalance?

Tanwar

Mattoo

Kumar

et al. 2018

Asian J Pharm Clin Res

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Objectives: The present study was conducted to estimate cortisol and thyroid-stimulating hormone (TSH) levels in patients with fibromyalgia syndrome (FMS) and to find correlation if any between hormone levels and pain duration in FMS.Methods: Plasma cortisol and TSH concentration were determined by electro chemiluminescence immunoassay in 89 female patients with FMS and 74 age-matched healthy women.Results: No significant difference in TSH level was observed between FMS and healthy subjects. Ten patients had higher cortisol levels than the standard reference range, 48 patients with reduced cortisol and 31 patients with normal cortisol levels. No significant correlation was observed between pain duration and levels of cortisol. Conclusion:The study has confirmed the equivocal data regarding cortisol/hypothalamic-pituitary-adrenal axis related dysfunction in FMS. To the best of our knowledge, it is the first Indian study on FMS which assessed the cortisol and TSH levels and their correlation with pain duration if any.

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Cortisol awakening rise in middle-aged women in relation to psychological stress

Cited by 81 publications

References 51 publications

Associations of Long-term Shift Work with Waking Salivary Cortisol Concentration and Patterns among Police Officers

Associations of Long-term Shift Work with Waking Salivary Cortisol Concentration and Patterns among Police Officers

Exploring day-to-day dynamics of daily stressor appraisals, physical symptoms and the cortisol awakening response

Is Fibromyalgia a Syndrome of Hormonal Imbalance?

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