“…In the case of animals successively given metopirone for 5 days, the profiles of in Rana esculenta (QUATTRINI, 1960;DUPONT, 1967DUPONT, , 1968, Rana temporaria (KEMENADE and DONGEN, 1967;KEMENADE, 1969a, b;LARSEN et al 1971). Using the electron microscope, the corticotroph cell was identified by several authors in various mammals; rat (FARQUHAR, 1957;HERLANT and KLASTERSKY, 1963;SIPERSTEIN and ALLISON, 1965;KUROSUMI and KOBAYASHI, 1966;KUROSUMI and OOTA, 1966;NAKAYAMA et al, 1969;NAKANE, 1970;PELLETIER, 1970;SIPERSTEIN and MILLER, 1970;PELLETIER and RACADOT, 1971), mouse (YAMADA and YAMASHITA, 1967), human (FONCIN and LE BEAU, 1964).…”