Corticosteroid therapy in traumatic shock

Alho, A; Karaharju, Erkki; Avikainen, Veikko; Jäättelä, A; Lahdensuu, M; Lepistö, P; Rokkanen, P; Tervo, Timo

doi:10.1016/0300-9572(74)90004-5

Cited by 3 publications

(3 citation statements)

References 9 publications

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“…Some researchers (22)(23)(24) reported that corticosteroids can be used in trauma patients, emphasizing that they increase cardiac output, decrease systemic and pulmonary vascular resistance, increase tissue perfusion and decrease the incidence of pulmonary thromboembolism. However, some researchers (25,26) argued that it may cause traumatic shock, increase morbidity and mortality by causing an increase in hyperglycemia, pneumonia risk and blood urea level in trauma patients, and did not recommend its use in trauma patients. They also emphasized that more studies are needed on the use of corticosteroids in trauma patients.…”

Section: Discussionmentioning

confidence: 99%

Clinical and etiologically evaluation of cats with high-rise syndrome: assessment of 72 cases (A retrospective study)

ÇATALKAYA

Altan

Kanay

et al. 2022

Veterinary Journal of Mehmet Akif Ersoy University

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Surgical problems observed in cats after falling from balconies or windows of buildings are significant, and this phenomenon of falling from a height is known as high-rise syndrome (HRS). The purpose of this study was to clinically evaluate frequently encountered cases of cats falling from a height. Overall, 72 cats of different breeds, ages and sexes brought to XXX University, Faculty of Veterinary Medicine, Department of Surgery, with complaints of falls from a height in 2019 were included. Falls from a height are more common during summer. Orthopaedic problems are common (58.33%), and femoral fractures (23.61%) constitute an important part of them. The affected cats were aged mostly under the 1 year. Furthermore, the survival rate of these cats was found to be 95.8%. In conclusion, the main purpose for the treatment of cats with HRS should be to stabilise their general condition and subsequently correct orthopaedic and/or soft tissue damage.

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Section: Discussionmentioning

confidence: 99%

Clinical and etiologically evaluation of cats with high-rise syndrome: assessment of 72 cases (A retrospective study)

ÇATALKAYA

Altan

Kanay

et al. 2022

Veterinary Journal of Mehmet Akif Ersoy University

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“…4,[9][10][11][12] The marked increase in catecholamine levels using the decapitation method has been suspected to be due to the activation of adrenal tyrosine hydoxylase, the rate-limiting enzyme in the synthesis of catecholamines 22) and sympathoadrenal activation due to acute hemorrhage. 23,24) In contrast, it is thought that plasma DOPAC levels were less affected by decapitation, as the change in plasma DOPAC levels did not depend on adrenal tyrosine hydoxylase activity 4) and there was a time lag in the metabolism of DA to DOPAC. It is known that DOPAC levels measured in rat plasma using the decapitation method were increased by immobilization stress, 4) as occurred with RWI in the present study.…”

Section: Discussionmentioning

confidence: 99%

Increases in Plasma Dihydroxyphenylacetic Acid Levels in Decapitated Mice after Exposure to Various Stresses.

Harikai

Fujii

Onodera

et al. 2002

Biological & Pharmaceutical Bulletin

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This study investigated changes in plasma levels of the dopamine metabolite dihydroxyphenylacetic acid (DOPAC) in decapitated mice in response to the variable stresses of restraint, restraint and water immersion, and foot shock. DOPAC levels, but not norepinephrine (NE) and epinephrine (EPI) levels, increased upon exposure to these stresses. Plasma DOPAC levels measured using the decapitation method in rats were then compared with those measured using the catheter method. The NE and EPI levels in plasma measured using the decapitation method were much higher than those using the catheter method under basal conditions. In contrast, differences in the levels of DOPAC in plasma were smaller than those of NE and EPI under basal conditions using in both methods; furthermore parallel changes in plasma DOPAC levels occurred during restraint and water immersion stresses. These results indicate that the plasma DOPAC levels measured in mice using the decapitation method were clearly increased by the different stresses. Furthermore, in rats there were correlations between the decapitation and catheter methods for plasma levels of DOPAC. Thus the change in plasma DOPAC levels measured using the decapitation method is a good indicator of stress responses involving sympathoneural activity.

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“…Other trials have failed to show these benefits or a survival advantage associated with GC administration . GC‐mediated adverse effects in traumatic shock include eosinophil granulocyte depression, sodium retention, hyperglycemia, gastrointestinal ulceration, increased blood urea nitrogen, and increased risk of pneumonia …”

Section: Glucocorticoids In Trauma and Hemorrhagic Shockmentioning

confidence: 99%

A review of associated controversies surrounding glucocorticoid use in veterinary emergency and critical care

Aharon

Prittie

Buriko

2017

J Vet Emergen Crit Care

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Corticosteroid therapy in traumatic shock

Cited by 3 publications

References 9 publications

Clinical and etiologically evaluation of cats with high-rise syndrome: assessment of 72 cases (A retrospective study)

Clinical and etiologically evaluation of cats with high-rise syndrome: assessment of 72 cases (A retrospective study)

Increases in Plasma Dihydroxyphenylacetic Acid Levels in Decapitated Mice after Exposure to Various Stresses.

A review of associated controversies surrounding glucocorticoid use in veterinary emergency and critical care

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