Corticosteroid-Induced Uveitis

The problem of uveitis in Bendel State of Nigeria: experience in Benin City.

“…Several factors other than racial have a part to play in the genesis of this condition (Mann, 1961). No patients with heterochromic cyclitis or the Vogt-Koyanagi-Harada syndrome have been seen, nor have cases of uveitis induced by dexamethasone sodium sulphate been encountered (Martins et al, 1974).…”

Drug-induced uveitis

“…There are several reports of uveitis developing or worsening in otherwise non-inflamed eyes during or immediately following withdrawal of topical corticosteroids [104-106]. Although earlier reports mainly indicated dexamethasone sodium phosphate 0.1%, corticosteroid withdrawal-associated uveitis has been described with different topical corticosteroid formulations, including prednisolone acetate 1% and dexamethasone 0.1% [104,105,107].…”

“…Although earlier reports mainly indicated dexamethasone sodium phosphate 0.1%, corticosteroid withdrawal-associated uveitis has been described with different topical corticosteroid formulations, including prednisolone acetate 1% and dexamethasone 0.1% [104,105,107]. …”

“…The uveitis responded to intensive treatment with the same agent along with a cycloplegic/mydriatic medication. The largest report is a case series of 16 patients without a prior history of uveitis and without a history of predisposing systemic conditions, who developed anterior uveitis associated with the withdrawal of topical corticosteroids [104]. Fifteen of the cases (94%) were associated with dexamethasone sodium phosphate 0.1%, with the remaining case associated with triamcinolone acetonide 0.5% ointment.…”

A review of evidence guiding the use of corticosteroids in the treatment of intraocular inflammation

“…The pharmacology and side effects of corticosteroids have been previously addressed elsewhere; no attempt is made to duplicate those efforts in this review. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] available corticosteroid formulations The most commonly used corticosteroids in ophthalmic practice are listed in Tables 1 and 2. The pharmacology of the currently available agents employed in the treatment of intraocular inflammatory disease has been exhaustively reviewed in other publications.…”