Corticospinal excitability during motor imagery of a simple tonic finger movement in patients with writer's cramp

Quartarone, Angelo; Bagnato, Sergio; Rizzo, Vincenzo; Morgante, Francesca; Sant’Angelo, Antonino; Crupi, Domenica; Romano, Marcello; Messina, C; Berardelli, Alfredo; Girlanda, Paolo

doi:10.1002/mds.20626

Cited by 49 publications

(32 citation statements)

References 39 publications

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“…In Parkinson’s patients the typical cortico-spinal excitability in response to the imagination of a movement is drastically reduced with respect to healthy controls (Tremblay et al, 2008). With regard to FHD patients, Quartarone et al (2005) delivered the TMS pulse while participants were imagining index flexion. Similarly to the results shown by Sohn and Hallet (2004) on movement execution, during motor imagery the amplitude of motor-evoked potentials of all recorded hand and forearm surround muscles was increased in FHD patients, even for the arm not involved in motor imagery (Quartarone et al, 2005).…”

Section: Mental Imagery and Rotation As “Clean” Tools To Investigate mentioning

confidence: 99%

“…With regard to FHD patients, Quartarone et al (2005) delivered the TMS pulse while participants were imagining index flexion. Similarly to the results shown by Sohn and Hallet (2004) on movement execution, during motor imagery the amplitude of motor-evoked potentials of all recorded hand and forearm surround muscles was increased in FHD patients, even for the arm not involved in motor imagery (Quartarone et al, 2005). This highlights the broad and less focused muscular activity in FHD patients compared with healthy subjects, even in the case of simply imagined movements.…”

Section: Mental Imagery and Rotation As “Clean” Tools To Investigate mentioning

confidence: 99%

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Focal dystonia and the Sensory-Motor Integrative Loop for Enacting (SMILE)

Perruchoud

Murray

Lefebvre

et al. 2014

Front. Hum. Neurosci.

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Performing accurate movements requires preparation, execution, and monitoring mechanisms. The first two are coded by the motor system, the latter by the sensory system. To provide an adaptive neural basis to overt behaviors, motor and sensory information has to be properly integrated in a reciprocal feedback loop. Abnormalities in this sensory-motor loop are involved in movement disorders such as focal dystonia, a hyperkinetic alteration affecting only a specific body part and characterized by sensory and motor deficits in the absence of basic motor impairments. Despite the fundamental impact of sensory-motor integration mechanisms on daily life, the general principles of healthy and pathological anatomic–functional organization of sensory-motor integration remain to be clarified. Based on the available data from experimental psychology, neurophysiology, and neuroimaging, we propose a bio-computational model of sensory-motor integration: the Sensory-Motor Integrative Loop for Enacting (SMILE). Aiming at direct therapeutic implementations and with the final target of implementing novel intervention protocols for motor rehabilitation, our main goal is to provide the information necessary for further validating the SMILE model. By translating neuroscientific hypotheses into empirical investigations and clinically relevant questions, the prediction based on the SMILE model can be further extended to other pathological conditions characterized by impaired sensory-motor integration.

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Section: Mental Imagery and Rotation As “Clean” Tools To Investigate mentioning

confidence: 99%

Section: Mental Imagery and Rotation As “Clean” Tools To Investigate mentioning

confidence: 99%

Focal dystonia and the Sensory-Motor Integrative Loop for Enacting (SMILE)

Perruchoud

Murray

Lefebvre

et al. 2014

Front. Hum. Neurosci.

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“…stroke victims 23 and patients suffering from writer's cramp. 24 Based on the study by Marshall et al, 3 we hypothesized that patients with a functional paresis would not be able to enhance motor excitability during imagery of movements with the affected body part, but that imagery of movements with a non-affected extremity would produce a similar excitability increase as in healthy subjects.…”

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confidence: 99%

Electrophysiological correlates of motor conversion disorder

et al. 2008

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In patients with a functional (psychogenic) paresis, motor conduction tests are, by definition, normal. We investigated whether these patients exhibit an abnormal motor excitability. Four female patients with a functional paresis of the left upper extremity were studied using transcranial magnetic stimulation (TMS). We investigated motor thresholds, intracortical inhibition and intracortical facilitation at rest. Corticospinal excitability was evaluated by single pulse TMS during rest and during imagination of tonic index finger adductions. Data obtained from the affected first dorsal interosseous muscle were compared with the unaffected hand and with a healthy age-matched control group. Three patients demonstrated a flaccid paresis, one patient had a psychogenic dystonia. Motor thresholds, short interval intracortical inhibition and intracortical facilitation recorded from the affected side were normal. In healthy subjects, movement imagination produced an increase of corticospinal excitability. In the patients, motor imagery with the affected index finger resulted in a decrease of corticospinal excitability compared to rest, being significantly different from the unaffected side and from the control group. We suggest that suppression of corticospinal excitability during movement imagination is an electrophysiological correlate of the patients' inability to move voluntarily and provides some insight into the pathophysiology of this disorder.2008 Movement Disorder Society

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“…an increase in the relative amount of irrelevant information, is very different from definitions of stress that emphasize the degree of activation of the autonomic nervous system [20]. These observations raise the possibility that the altered brain activation during MI observed for patients with diseases of the nervous system such as apraxia [69], Parkinson's disease [70] and writer's cramp [71], may be in part relate to difficulties that such individuals have in filtering out irrelevant information.…”

Section: Performancementioning

confidence: 63%

Imaging motor imagery: Methodological issues related to expertise

Milton

Small

Solodkin

2008

Methods

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Mental imagery (MI) is the mental rehearsal of movements without overt execution. Brain imaging techniques have made it possible to identify the brain regions that are activated during MI and, for voluntary motor tasks involving hand and finger movements, to make direct comparison with those areas activated during actual movement. However, the fact that brain activation differs for different types of imagery (visual or kinetic) and depends on the skill level of the individual (e.g. novice or elite athlete) raises a number of important methodological issues for the design of brain imaging protocols to study MI. These include instructing the subject concerning the type of imagery to use, objective measurement of skill level, the design of motor tasks sufficiently difficult to produce a range of skill levels, the effect of different environments on skill level (including the imaging device), and so on. It is suggested that MI is more about the neurobiology of the development of motor skills that have already been learned, but not perfected, than it is about learning motor skills de novo.

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Corticospinal excitability during motor imagery of a simple tonic finger movement in patients with writer's cramp

Cited by 49 publications

References 39 publications

Focal dystonia and the Sensory-Motor Integrative Loop for Enacting (SMILE)

Focal dystonia and the Sensory-Motor Integrative Loop for Enacting (SMILE)

Electrophysiological correlates of motor conversion disorder

Imaging motor imagery: Methodological issues related to expertise

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