Corticofugal modulation of directional sensitivity in the midbrain of the big brown bat, Eptesicus fuscus

Zhou, Xiaoming; Jen, Philip H.‐S.

doi:10.1016/j.heares.2004.12.008

Cited by 41 publications

(21 citation statements)

References 88 publications

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“…Cortical projections have been identified to all major brainstem auditory loci, including the CN (e.g., Schofield and Coomes, 2005). Descending connections have been implicated in auditory selective attention, and shown to modulate basic response properties such as excitatory threshold and interaural level difference-and frequency-tuning of neurons at various central auditory loci (Nakamoto et al, 2008;Suga and Ma, 2003;Suga et al, 2000;Yan and Suga, 1996a,b;Yan and Suga, 1999;Yan et al, 2005;Zhou and Jen, 2005).…”

Section: Discussionmentioning

confidence: 99%

Equivalent-rectangular bandwidth of single units in the anaesthetized guinea-pig ventral cochlear nucleus

Sayles

Winter

2010

Hearing Research

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Section: Discussionmentioning

confidence: 99%

Equivalent-rectangular bandwidth of single units in the anaesthetized guinea-pig ventral cochlear nucleus

Sayles

Winter

2010

Hearing Research

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“…In the IC, neuronal sensitivity to sound frequency (Ma and Suga, 2001a; Yan et al, 2005), intensity (Yan and Ehret, 2002), duration (Ma and Suga, 2001b), and location (Zhou and Jen, 2005; Nakamoto et al, 2008) changes after manipulating activity in A1 (Figures 7, 8). Thus, the descending system can shape the way midbrain neurons respond to stimulus attributes, such as sound frequency or intensity, which are initially encoded in the cochlea, as well as those that rely on central processing, like sound source location.…”

Section: Corticofugal Modulation Of Auditory Processing In the Inferimentioning

confidence: 99%

Cortical modulation of auditory processing in the midbrain

Bajo¹,

King²

2013

Front. Neural Circuits

107

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In addition to their ascending pathways that originate at the receptor cells, all sensory systems are characterized by extensive descending projections. Although the size of these connections often outweighs those that carry information in the ascending auditory pathway, we still have a relatively poor understanding of the role they play in sensory processing. In the auditory system one of the main corticofugal projections links layer V pyramidal neurons with the inferior colliculus (IC) in the midbrain. All auditory cortical fields contribute to this projection, with the primary areas providing the largest outputs to the IC. In addition to medium and large pyramidal cells in layer V, a variety of cell types in layer VI make a small contribution to the ipsilateral corticocollicular projection. Cortical neurons innervate the three IC subdivisions bilaterally, although the contralateral projection is relatively small. The dorsal and lateral cortices of the IC are the principal targets of corticocollicular axons, but input to the central nucleus has also been described in some studies and is distinctive in its laminar topographic organization. Focal electrical stimulation and inactivation studies have shown that the auditory cortex can modify almost every aspect of the response properties of IC neurons, including their sensitivity to sound frequency, intensity, and location. Along with other descending pathways in the auditory system, the corticocollicular projection appears to continually modulate the processing of acoustical signals at subcortical levels. In particular, there is growing evidence that these circuits play a critical role in the plasticity of neural processing that underlies the effects of learning and experience on auditory perception by enabling changes in cortical response properties to spread to subcortical nuclei.

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“…The larger the difference in BAZ between them, the larger the centripetal BAZ shift (Fig. 7f; Zhou and Jen 2005). …”

Section: (3) Corticofugal Modulation: the Primary Auditory Cortex To mentioning

confidence: 99%

“…Their BAZs shift toward the midline, i.e., toward the BAZs of the stimulated cortical neurons. L, lateral; M, medial (Zhou and Jen 2005). The MT and BAZ shifts are linearly related to the difference in MT and BAZ between the recorded collicular (ICc r ) and stimulated cortical (AI s ) neurons, respectively.…”

Section: Figmentioning

confidence: 99%

Tuning shifts of the auditory system by corticocortical and corticofugal projections and conditioning

Suga

2012

Neuroscience & Biobehavioral Reviews

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The central auditory system consists of the lemniscal and nonlemniscal systems. The thalamic lemniscal and non-lemniscal auditory nuclei are different from each other in response properties and neural connectivities. The cortical auditory areas receiving the projections from these thalamic nuclei interact with each other through corticocortical projections and project down to the subcortical auditory nuclei. This corticofugal (descending) system forms multiple feedback loops with the ascending system. The corticocortical and corticofugal projections modulate auditory signal processing and play an essential role in the plasticity of the auditory system. Focal electric stimulation -- comparable to repetitive tonal stimulation -- of the lemniscal system evokes three major types of changes in the physiological properties, such as the tuning to specific values of acoustic parameters of cortical and subcortical auditory neurons through different combinations of facilitation and inhibition. For such changes, a neuromodulator, acetylcholine, plays an essential role. Electric stimulation of the nonlemniscal system evokes changes in the lemniscal system that is different from those evoked by the lemniscal stimulation. Auditory signals ascending from the lemniscal and nonlemniscal thalamic nuclei to the cortical auditory areas appear to be selected or adjusted by a “differential” gating mechanism. Conditioning for associative learning and pseudo-conditioning for nonassociative learning respectively elicit tone-specific and nonspecific plastic changes. The lemniscal, corticofugal and cholinergic systems are involved in eliciting the former, but not the latter. The current article reviews the recent progress in the research of corticocortical and corticofugal modulations of the auditory system and its plasticity elicited by conditioning and pseudo-conditioning.

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Corticofugal modulation of directional sensitivity in the midbrain of the big brown bat, Eptesicus fuscus

Cited by 41 publications

References 88 publications

Equivalent-rectangular bandwidth of single units in the anaesthetized guinea-pig ventral cochlear nucleus

Equivalent-rectangular bandwidth of single units in the anaesthetized guinea-pig ventral cochlear nucleus

Cortical modulation of auditory processing in the midbrain

Tuning shifts of the auditory system by corticocortical and corticofugal projections and conditioning

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