Cortical Vision Loss as a Prominent Feature of H1N1 Encephalopathy

Pula, John H.; Issawi, Ahmad; DeSanto, Jeffrey; Kattah, Jorge C.

doi:10.1097/wno.0b013e31823fd913

Cited by 9 publications

(6 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There have been 28 reported cases of IAE in adults with 7 further differentiating the clinical syndromes including 3 cases of PRES, 2 cases of MERS, and 2 cases of AHLE (Table ) . In these reports, men are more often affected (19/28; 68%) and patients range in age between 20 and 86 years old.…”

Section: Resultsmentioning

confidence: 99%

The hidden burden of influenza: A review of the extra‐pulmonary complications of influenza infection

Sellers

Hagan

Hayden

et al. 2017

Influenza Resp Viruses

323

308

View full text Add to dashboard Cite

Severe influenza infection represents a leading cause of global morbidity and mortality. Although influenza is primarily considered a viral infection that results in pathology limited to the respiratory system, clinical reports suggest that influenza infection is frequently associated with a number of clinical syndromes that involve organ systems outside the respiratory tract. A comprehensive MEDLINE literature review of articles pertaining to extra‐pulmonary complications of influenza infection, using organ‐specific search terms, yielded 218 articles including case reports, epidemiologic investigations, and autopsy studies that were reviewed to determine the clinical involvement of other organs. The most frequently described clinical entities were viral myocarditis and viral encephalitis. Recognition of these extra‐pulmonary complications is critical to determining the true burden of influenza infection and initiating organ‐specific supportive care.

show abstract

Section: Resultsmentioning

confidence: 99%

The hidden burden of influenza: A review of the extra‐pulmonary complications of influenza infection

Sellers

Hagan

Hayden

et al. 2017

Influenza Resp Viruses

323

308

View full text Add to dashboard Cite

show abstract

“…A total of 115 articles were initially retrieved, but eleven of them were eliminated according to our exclusion criteria. Finally, considering our inclusion criteria, only 104 articles (1636 patients) were included and divided into two groups, according to the origin of neurological complications: influenza vaccine‐related (287 patients) or viral infection‐related (1349 patients) (Tables S1 and S2) . The main characteristics of patients are summarized in Table .…”

Section: Resultsmentioning

confidence: 99%

Neurological events related to influenza A (H1N1) pdm09

Cárdenas

Soto-Hernández

Díaz-Alba

et al. 2014

Influenza Resp Viruses

View full text Add to dashboard Cite

ObjectivesTo review neurological complications after the influenza A (H1N1) pdm09, highlighting the clinical differences between patients with post-vaccine or viral infection.DesignA search on Medline, Ovid, EMBASE, and PubMed databases using the keywords “neurological complications of Influenza AH1N1” or “post-vaccine Influenza AH1N1.”SettingOnly papers written in English, Spanish, German, French, Portuguese, and Italian published from March 2009 to December 2012 were included.SampleWe included 104 articles presenting a total of 1636 patient cases. In addition, two cases of influenza vaccine-related neurological events from our neurological care center, arising during the period of study, were also included.Main outcome measuresDemographic data and clinical diagnosis of neurological complications and outcomes: death, neurological sequelae or recovery after influenza A (H1N1) pdm09 vaccine or infection.ResultsThe retrieved cases were divided into two groups: the post-vaccination group, with 287 patients, and the viral infection group, with 1349 patients. Most patients in the first group were adults. The main neurological complications were Guillain-Barre syndrome (GBS) or polyneuropathy (125), and seizures (23). All patients survived. Pediatric patients were predominant in the viral infection group. In this group, 60 patients (4.7%) died and 52 (30.1%) developed permanent sequelae. A wide spectrum of neurological complications was observed.ConclusionsFatal cases and severe, permanent, neurological sequelae were observed in the infection group only. Clinical outcome was more favorable in the post-vaccination group. In this context, the relevance of an accurate neurological evaluation is demonstrated for all suspicious cases, as well as the need of an appropriate long-term clinical and imaging follow-up of infection and post-vaccination events related to influenza A (H1N1) pdm09, to clearly estimate the magnitude of neurological complications leading to permanent disability.

show abstract

“…Optic neuritis has been reported with steroid therapy improving the condition [210,216,218]. Reports of encephalopathy associated with cortical visual loss and oculomotor palsy is also possible [219][220][221].…”

Section: Influenza a H1n1 (Orthomyxoviridae)mentioning

confidence: 99%

Ocular manifestations of emerging viral diseases

Venkatesh

Patel

Goyal

et al. 2021

Eye

View full text Add to dashboard Cite

Emerging infectious diseases (EIDs) are an increasing threat to public health on a global scale. In recent times, the most prominent outbreaks have constituted RNA viruses, spreading via droplets (COVID-19 and Influenza A H1N1), directly between humans (Ebola and Marburg), via arthropod vectors (Dengue, Zika, West Nile, Chikungunya, Crimean Congo) and zoonotically (Lassa fever, Nipah, Rift Valley fever, Hantaviruses). However, specific approved antiviral therapies and vaccine availability are scarce, and public health measures remain critical. Patients can present with a spectrum of ocular manifestations. Emerging infectious diseases should therefore be considered in the differential diagnosis of ocular inflammatory conditions in patients inhabiting or returning from endemic territories, and more general vigilance is advisable in the context of a global pandemic. Eye specialists are in a position to facilitate swift diagnosis, improve clinical outcomes, and contribute to wider public health efforts during outbreaks. This article reviews those emerging viral diseases associated with reports of ocular manifestations and summarizes details pertinent to practicing eye specialists.

show abstract

Cortical Vision Loss as a Prominent Feature of H1N1 Encephalopathy

Cited by 9 publications

References 17 publications

The hidden burden of influenza: A review of the extra‐pulmonary complications of influenza infection

The hidden burden of influenza: A review of the extra‐pulmonary complications of influenza infection

Neurological events related to influenza A (H1N1) pdm09

Ocular manifestations of emerging viral diseases

Contact Info

Product

Resources

About