Cortical lateralization in stroke patients measured by event-related potentials during motor imagery

Abstract

Abstract. Stroke is a leading cause of impairment and disability worldwide, and motor imagery (MI) has been used in stroke rehabilitation. Electroencephalography (EEG) has been used to study MI. However, the characteristic features of EEG during MI in stroke patients have not been established. The purpose of this study was to investigate the difference in event-related potentials (ERPs) during MI between healthy controls and stroke patients. This study included nine stroke patients and nine healthy age-matched controls, who performed tasks involving MI, passive movement without MI and passive movement with MI. One hundred and twenty-eight channel ERPs were recorded to capture cerebral activation. Electrodes E44 and E120 (corresponding to the inferior precentral area) were selected to analyze the lateralization effects of ERPs. Lateralization was calculated as the ratio of the potential at 500 ms at electrode E120 to that at electrode E44. In the controls, the different ERPs exhibited differential direction between the 0-300 and the 300-700 ms interval. ERPs were evoked by passive movement with MI and MI alone, but not passive movement without MI. In addition, a lateralization effect in control patients as shown by the observation that the lateralization ratio in passive movement with MI and MI alone was significantly different from that in passive movement without MI (P<0.05). The amplitudes of the different ERPs were significantly smaller in stroke patients compared with those in the controls (P<0.05). The lateralization ratio in the stroke patients was opposite and significantly different from that of the controls (P<0.05). The results suggested that the MI-induced lateralization effect in ERPs may be used as a measure for evaluating the MI impairment and recovery in stroke patients.

EEG response varies with lesion location in patients with chronic stroke

“…Therefore, we expect that using both the ERD magnitude and LC metrics will lead to a better understanding of neural activities according to lesion location in stroke patients. In a previous study, Gong et al have shown that patients with stroke exhibit different LC patterns of event-related potentials while performing motor imagery tasks compared with those of HCs [ 26 ]. Kaiser et al also have investigated the relationship between the LC of ERS and motor function ability [ 23 ].…”

A Hybrid FPGA-Based System for EEG- and EMG-Based Online Movement Prediction

“…Secondly, the current study was conducted using healthy subjects. Although it has been shown that patients that suffer from, e.g., stroke, are feasible to perform movement-imagination despite chronic or severe motor impairments [ 68 , 69 , 164 ], different kinds of brain damages can affect the EEG [ 165 , 166 , 167 , 168 , 169 , 170 ] and EMG [ 171 , 172 ], and hence, possibly the performance of the proposed system. However, MRCP-based BCIs can be successfully used by patients suffering from stroke [ 173 , 174 , 175 ].…”

Poststroke Upper Limb Recovery

“…In addition, there may also be some differences in lateralization characteristics after a stroke. 60 An analysis of mental practice and motor imagery studies involving UE training of patients poststroke concluded, when combined with physical practice, mental practice with motor imagery has a significant positive effect on arm-hand activities, but nonsignificant effects for motor function, muscle strength, or basic ADLs. 9 Interesting New Developments in the Therapeutic Pipeline…”