Cortical gradient perturbation in attention deficit hyperactivity disorder correlates with neurotransmitter‐, cell type‐specific and chromosome‐ transcriptomic signatures
Zhiyi Chen,
Ting Xu,
Xuerong Liu
et al.
Abstract:AimsThis study aimed to illuminate the neuropathological landscape of attention deficit hyperactivity disorder (ADHD) by a multiscale macro–micro‐molecular perspective from in vivo neuroimaging data.MethodsThe “ADHD‐200 initiative” repository provided multi‐site high‐quality resting‐state functional connectivity (rsfc‐) neuroimaging for ADHD children and matched typically developing (TD) cohort. Diffusion mapping embedding model to derive the functional connectome gradient detecting biologically plausible neur… Show more
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