Cortical deafness of following bilateral temporal lobe stroke

Silva, Júlia; Sousa, Marisa; Mestre, Susana; Nzwalo, Isa; Nzwalo, Hipólito

doi:10.1016/j.jstrokecerebrovasdis.2020.104827

Cited by 10 publications

(4 citation statements)

References 11 publications

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“…A total of 103 manuscripts was selected for a complete text evaluation, after which 44 were included [ 2 , 4 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 ]. The total number of patients included was 46 ( Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

“…The duration of the follow-up varied from 2 weeks to 15 years. A substantial part of the patients did not improve, and remained with a persistent inability to recognize any sound at all (16/34.8%) [ 2 , 8 , 12 , 15 , 16 , 17 , 18 , 19 , 29 , 33 , 34 , 35 , 37 , 43 , 46 , 48 ], while others evolved to pure word deafness (11/36.6%) [ 7 , 9 , 10 , 11 , 13 , 18 , 21 , 22 , 24 , 31 , 36 , 39 , 41 , 42 ]. Oral conversation was regained in six (20%) of the patients [ 7 , 20 , 25 , 27 , 28 , 32 , 42 , 43 ].…”

Section: Resultsmentioning

confidence: 99%

“…This systematic review confirmed the extreme rarity of stroke-associated CD. However, because alternative diagnoses, such as peripheral hearing disease or even psychiatric disorder [ 2 , 29 , 36 ], were reported, the possibility of a misdiagnosis should be considered. The coexistence of CD with language impairment, in particular with Wernicke’s aphasia, is a reality [ 49 ] and may further complicate prompt recognition.…”

Section: Discussionmentioning

confidence: 99%

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Stroke-Associated Cortical Deafness: A Systematic Review of Clinical and Radiological Characteristics

et al. 2021

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Background: Stroke is the leading cause of cortical deafness (CD), the most severe form of central hearing impairment. CD remains poorly characterized and perhaps underdiagnosed. We perform a systematic review to describe the clinical and radiological features of stroke-associated CD. Methods: PubMed and the Web of Science databases were used to identify relevant publications up to 30 June 2021 using the MeSH terms: “deafness” and “stroke”, or “hearing loss” and “stroke” or “auditory agnosia” and “stroke”. Results: We found 46 cases, caused by bilateral lesions within the central auditory pathway, mostly located within or surrounding the superior temporal lobe gyri and/or the Heschl’s gyri (30/81%). In five (13.51%) patients, CD was caused by the subcortical hemispheric and in two (0.05%) in brainstem lesions. Sensorineural hearing loss was universal. Occasionally, a misdiagnosis by peripheral or psychiatric disorders occurred. A few (20%) had clinical improvement, with a regained oral conversation or evolution to pure word deafness (36.6%). A persistent inability of oral communication occurred in 43.3%. A full recovery of conversation was restricted to patients with subcortical lesions. Conclusions: Stroke-associated CD is rare, severe and results from combinations of cortical and subcortical lesions within the central auditory pathway. The recovery of functional hearing occurs, essentially, when caused by subcortical lesions.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Stroke-Associated Cortical Deafness: A Systematic Review of Clinical and Radiological Characteristics

et al. 2021

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“…Cortical deafness is a clinical rarity whereby auditory signals cannot be perceived by the auditory cortex despite preserved integrity of the peripheral hearing organs, as mentioned by Silva, et al [ 1 ]. In this condition, a patient is unresponsive to all types of sounds caused by lesions in the central auditory nervous system.…”

Section: Introductionmentioning

confidence: 99%

Cortical Deafness Due to Ischaemic Strokes in Both Temporal Lobes

et al. 2021

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Cortical deafness is a clinical rarity whereby a patient is unresponsive to all types of sounds despite the preserved integrity of the peripheral hearing organs. In this study, we present a patient who suddenly lost his hearing following ischaemic infarcts in both temporal lobes with no other neurological deficits. The CT confirmed damage to the primary auditory cortex (Heschl's gyrus) of both hemispheres. Initially, the patient was unresponsive to all sounds, however, he regained some of the auditory abilities during 10 months follow up. Pure tone threshold improvement from complete deafness to the level of moderate hearing loss in the right ear and severe in the left was observed in pure tone audiometry. Otoacoustic emissions, auditory brainstem responses, and acoustic reflex findings showed normal results. The middle and late latency potential results confirmed objectively the improvement of the patient's hearing, however, after 10 months still, they were somewhat compromised on both sides. In speech audiometry, there was no comprehension of spoken words neither at 3 nor at 10 months. The absent mismatch negativity confirmed above mentioned comprehension deficit. The extensive auditory electrophysiological testing presented in this study contributes to the understanding of the neural and functional changes in cortical deafness. It presents the evolution of changes after ischaemic cerebrovascular event expressed as auditory evoked potentials starting from short through middle and long latency and ending with event-related potentials and supported by neuroimaging.

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The Auditory Agnosias: a Short Review of Neurofunctional Evidence

Miceli,

Caccia

2023

Curr Neurol Neurosci Rep

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Purpose of Review To investigate the neurofunctional correlates of pure auditory agnosia and its varieties (global, verbal, and nonverbal), based on 116 anatomoclinical reports published between 1893 and 2022, with emphasis on hemispheric lateralization, intrahemispheric lesion site, underlying cognitive impairments. Recent Findings Pure auditory agnosia is rare, and observations accumulate slowly. Recent patient reports and neuroimaging studies on neurotypical subjects offer insights into the putative mechanisms underlying auditory agnosia, while challenging traditional accounts. Summary Global auditory agnosia frequently results from bilateral temporal damage. Verbal auditory agnosia strictly correlates with language-dominant hemisphere lesions. Damage involves the auditory pathways, but the critical lesion site is unclear. Both the auditory cortex and associative areas are reasonable candidates, but cases resulting from brainstem damage are on record. The hemispheric correlates of nonverbal auditory input disorders are less clear. They correlate with unilateral damage to either hemisphere, but evidence is scarce. Based on published cases, pure auditory agnosias are neurologically and functionally heterogeneous. Phenotypes are influenced by co-occurring cognitive impairments. Future studies should start from these facts and integrate patient data and studies in neurotypical individuals.

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Cortical deafness of following bilateral temporal lobe stroke

Cited by 10 publications

References 11 publications

Stroke-Associated Cortical Deafness: A Systematic Review of Clinical and Radiological Characteristics

Stroke-Associated Cortical Deafness: A Systematic Review of Clinical and Radiological Characteristics

Cortical Deafness Due to Ischaemic Strokes in Both Temporal Lobes

The Auditory Agnosias: a Short Review of Neurofunctional Evidence

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