Cortical Blindness: A Rare but Dramatic Complication following Coronary Angiography

Gellen, Barnabas; Remp, T.; Mayer, Thomas O.; Milz, Petra; Franz, Wolfgang-M.

doi:10.1159/000068443

Cited by 16 publications

(8 citation statements)

References 6 publications

(8 reference statements)

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“…From the search results, we identified five case series and 38 case reports , for a total of 52 patients. The first published report documenting presumed CIE associated with cardiac catheterization dates from 1970 .…”

Section: Resultsmentioning

confidence: 99%

Contrast‐induced encephalopathy following cardiac catheterization

Spina

Simon

Markus

et al. 2016

Cathet Cardio Intervent

107

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M a i l i n g A d d r e s s : F r e d e r i c o T. U l t r a m a r i @@@@@@@@@@@@@@@@@@@@@@@@@@@ It is estimated that 6,000 and 2,000 cardiac catheterization procedures per million inhabitants/year are performed in Western countries for diagnostic and therapeutic purposes. In order to perform these procedures, 1,800 tons of iodine are required all over the world to manufacture contrast media (CM). The number of procedures that require the use of contrast media (or dye) has increased over time, and the population submitted to it is growing older, presenting more comorbidities 1, 2. Currently low-osmolar contrast media are used in approximately 75% of patients and the iso-osmolar contrast media, allegedly less toxic are becoming more popular 1. In spite of development of new contrast media, they still represent the third main cause of nosocomial-acquired acute renal failure (ARF) (10% of cases), substantially increasing hospitalization period, care costs and in-hospital morbi-mortality 3-6. The main goal is to address important aspects about the contrast-medium induced nephropathy (CMIN) that follows cardiac catheterization, including its definition, pathogenesis, incidence, risk factors, clinical picture, prevention, treatment and prognosis.

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Section: Resultsmentioning

confidence: 99%

Contrast‐induced encephalopathy following cardiac catheterization

Spina

Simon

Markus

et al. 2016

Cathet Cardio Intervent

107

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“…No particular management strategy has yet been proved effective for improving the natural history of transient cortical blindness following cerebral angiography (9, 26) However, physicians should be aware that transient cortical blindness is self-limiting and reversible. When it does occur, patients should be reassured of the excellent prognosis of this condition and that symptoms will resolve spontaneously within a few days.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors of Transient Cortical Blindness After Cerebral Angiography: A Multicenter Study

Liang

Liu

et al. 2019

Front. Neurol.

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Background: Although transient cortical blindness is a rare complication following cerebral angiography, identification of risk factors for the development of transient cortical blindness after cerebral angiography is an important clinical issue.Material and methods: Between January 2008 and April 2018, 5,126 patients at five high-volume medical centers who underwent cerebral angiography procedures were enrolled in this multicenter cohort study. Patient baseline characteristics and surgery-related factors were analyzed. We used multivariate logistic regression to examine factors associated with transient cortical blindness.Results: Eighteen patients (0.35%) in the total cohort of 5,126 suffered transient cortical blindness. After univariate statistical analysis, no significant differences were determined between the transient cortical blindness group and the control group regarding gender (p = 0.454), age (p = 0.872), smoking (p = 0.170), diabetes (p = 0.800), and hypertension (p = 0.100). Compared with the control group, the transient cortical blindness group weighed less (p = 0.020), and had a larger dose of contrast agent (p = 0.034) and more instances of contrast agent injected into the posterior circulation (p < 0.001). Logistic regression analysis identified contrast agent dose and contrast agent injected into posterior circulation as independent predictive factors for transient cortical blindness (P < 0.05).Conclusion: Larger doses off contrast agent and contrast agent injected into the posterior circulation are potential independent predictive factors for transient cortical blindness following cerebral angiography.

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“…In fact, no treatment has been proven to be effective to improve the natural history of TCB following cerebral angiography [6,10]. It usually lasts from a few hours to a few days.…”

Section: Discussionmentioning

confidence: 99%

Transient Cortical Blindness Following Vertebral Angiography: A Case Report

Lo¹,

Chan²,

Fai³

et al. 2015

Neurointervention

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Transient cortical blindness (TCB) is a rare but well-known complication of cerebral angiography. Its pathophysiology remains uncertain. We would like to report a case of TCB in a patient during a follow up vertebral angiogram for post-coil embolization of left posterior inferior cerebellar artery aneurysm. Patient's vision was resumed spontaneously within 24 hours after angiography, with no residual neurological deficit in subsequent clinical follow up. Multi-modality imaging evaluation including vertebral angiography, brain CT and MRI performed on same day are presented.

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Cortical Blindness: A Rare but Dramatic Complication following Coronary Angiography

Cited by 16 publications

References 6 publications

Contrast‐induced encephalopathy following cardiac catheterization

Contrast‐induced encephalopathy following cardiac catheterization

Risk Factors of Transient Cortical Blindness After Cerebral Angiography: A Multicenter Study

Transient Cortical Blindness Following Vertebral Angiography: A Case Report

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