Cortical and white matter correlates of language‐learning aptitudes

Novén, Mikael; Olsson, Hampus; Helms, Gunther; Horne, Merle; Nilsson, Markus; Roll, Mikael

doi:10.1002/hbm.25598

Cited by 8 publications

(3 citation statements)

References 89 publications

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“…DKI might be used to map diffusion properties related to tissue microstructure from language-related white matter tracts. Negative correlations were observed between scores for phonetic memory and MK, axial kurtosis, and radial kurtosis of the left superior longitudinal fasciculus III, which are tracts connecting cortical areas important for phonological working memory ( 22 ). An increasing motor activity level was also positively correlated with MK in the inferior, medial and superior longitudinal fasciculus, the corpus callosum and the posterior cingulum in schizophrenia.…”

Section: Discussionmentioning

confidence: 99%

Microstructural changes of white matter assessed with diffusional kurtosis imaging in extremely preterm infants with severe intraventricular hemorrhage

et al. 2022

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ObjectiveIntraventricular hemorrhage (IVH) is a serious neurological complication in premature infants. This study aimed to investigate the white matter impairments and neurodevelopmental outcomes of severe IVH in extremely preterm infants with gestation age less than 28 weeks.MethodsWe retrospectively evaluated the extremely preterm infants between 2017 and 2020. Neurodevelopmental outcomes were evaluated with the Bayley Scales of Infant and Toddler Development-III at 2 years of corrected age. Diffusional kurtosis imaging (DKI) was employed to evaluate the microstructural changes in white matter tracts. Mean kurtosis (MK) and fractional anisotropy (FA) values of DKI were measured in the brain regions including posterior limbs of the internal capsule (PLIC) and the corpus callosum at term equivalent age.ResultsOf 32 extremely preterm infants with severe IVH during the follow-up period, 18 cases were identified as neurodevelopmental impairments. The delay rates of motor and language were 58.4% and 52.7%. The cases with neurodevelopmental impairments had lower MK and FA values in both bilateral PLIC and the corpus callosum. The analysis of multivariable regression models predicting motor and language outcomes at 2 years of corrected age, showed that the decreases of MK values in both PLIC and the corpus callosum at the term equivalent age contributed to a significantly increased risk of neurodevelopmental impairments (all p < 0.05). During follow-up period, obvious loss of nerve fiber bundles was observed with DKI tractography.ConclusionMotor and language abilities at age 2 years were associated with MK values of DKI at the term equivalent age in both PLIC and the corpus callosum of extremely preterm infants with severe IVH. The evaluation of white matter microstructural changes with MK values might provide feasible indicators of neurodevelopmental outcomes of extremely preterm infants with severe intraventricular hemorrhage.

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Section: Discussionmentioning

confidence: 99%

Microstructural changes of white matter assessed with diffusional kurtosis imaging in extremely preterm infants with severe intraventricular hemorrhage

et al. 2022

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“…The 0.8 mm isotropic resolution protocol was previously used in a separate work to study correlations between cortical morphology and language-learning aptitude [ 19 ]. From the underlying subject population of this work, a subset of 10 randomly chosen volunteers (7 female, 22 ± 1.9 years old) were used to examine the inter-subject variability of the normalized MPRAGE images.…”

Section: Methodsmentioning

confidence: 99%

Radiofrequency Bias Correction of Magnetization Prepared Rapid Gradient Echo MRI at 7.0 Tesla Using an External Reference in a Sequential Protocol

et al. 2021

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At field strengths of 7 T and above, T1-weighted imaging of human brain suffers increasingly from radiofrequency (RF) B1 inhomogeneities. The well-known MP2RAGE (magnetization prepared two rapid acquisition gradient echoes) sequence provides a solution but may not be readily available for all MR systems. Here, we describe the implementation and evaluation of a sequential protocol to obtain normalized magnetization prepared rapid gradient echo (MPRAGE) images at 0.7, 0.8, or 0.9-mm isotropic spatial resolution. Optimization focused on the reference gradient-recalled echo (GRE) that was used for normalization of the MPRAGE. A good compromise between white-gray matter contrast and the signal-to-noise ratio (SNR) was reached at a flip angle of 3° and total scan time was reduced by increasing the reference voxel size by a factor of 8 relative to the MPRAGE resolution. The average intra-subject coefficient-of-variation (CV) in segmented white matter (WM) was 7.9 ± 3.3% after normalization, compared to 20 ± 8.4% before. The corresponding inter-subject average CV in WM was 7.6 ± 7.6% and 13 ± 7.8%. Maps of T1 derived from forward signal modelling showed no obvious bias after correction by a separately acquired flip angle map. To conclude, a non-interleaved acquisition for normalization of MPRAGE offers a simple alternative to MP2RAGE to obtain semi-quantitative purely T1-weighted images. These images can be converted to T1 maps, analogously to the established MP2RAGE approach. Scan time can be reduced by increasing the reference voxel size which has only a miniscule effect on image quality.

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“…Psychological factors are also factors that have a strong influence on early childhood reading skills (Getie, 2020). These factors include motivation, children's interest in books (Capellini & Germano, 2015), letters and other language symbols, and the child's selfadjusting attitude (Novén et al, 2021).…”

Section: Internal Factorsmentioning

confidence: 99%

Readiness to Learn English for Early Childhood

Sumarni

Vianty

Andika

2021

J. Obs. J. Pendidik. Anak Usia Dini

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Teachers need to understand the factors that influence the readiness of early childhood to learn their new language, especially English, to avoid inappropriate stimulation practices. This study aimed to examine early childhood English learning readiness factors based on relevant theories and research results. This research method was a qualitative literature review study. The literature review consists of 70 references related to the topic of early childhood English. This research method is a qualitative literature review study. As a result, children's readiness to learn is influenced by internal and external factors. Internal factors include cognitive abilities, mastery of the initial language, mastery of a new language, namely English, emotional maturity, and intrinsic motivation. At the same time, the external factors that influence include extrinsic motivation, family, social culture environment, and stimulation by playing.The novelty is to identify the influence of children's readiness factors in learning English both inside and outside the child. As a result, the teacher can consider the readiness of the child to avoid mistakes in introducing English as a new language for early childhood.

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Cortical and white matter correlates of language‐learning aptitudes

Cited by 8 publications

References 89 publications

Microstructural changes of white matter assessed with diffusional kurtosis imaging in extremely preterm infants with severe intraventricular hemorrhage

Microstructural changes of white matter assessed with diffusional kurtosis imaging in extremely preterm infants with severe intraventricular hemorrhage

Radiofrequency Bias Correction of Magnetization Prepared Rapid Gradient Echo MRI at 7.0 Tesla Using an External Reference in a Sequential Protocol

Readiness to Learn English for Early Childhood

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