Corrigendum to “The Antiosteoporosis Effects of Yishen Bugu Ye Based on Its Regulation on the Differentiation of Osteoblast and Osteoclast”

Li, Yangyang; Zhang, Yongfeng; Meng, Weiqi; Li, Yutong; Huang, Tao; Wang, Di; Hu, Min

doi:10.1155/2021/9824165

Cited by 1 publication

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“…Yi Shen Bu Gu liquid upregulated IL-33 and downregulated IL-1, IL-7, and TNF-α levels to reduce the inflammatory reaction and increased serum superoxide dismutase (SOD) and catalase (CAT) levels to reduce the oxidation reaction to inhibit OC formation. Li (2021) Bu Shen Qu Han Zhi Wang decoction suppressed OC activity through OPG/RANK/RANKL, reducing the expression of MMP-13, TNF-α, IL-1, IL-2, IL-17, and RANKL to cure RA Li et al (2017) ; Ma, (2021) ; Wu et al,(2018) ; Yan, (2012) ; ( Figure 2 ); ( Table 1 ). These traditional Chinese medicine formulae of tonifying kidney-yang herbs for osteoclastogenesis are preliminarily studied from the cytokines, but the potential immunoregulation mechanisms need to be further explored using immune cells.…”

Section: Immunoregulation Mechanisms By Which Tonifying Kidney-yang H...mentioning

confidence: 99%

Mechanisms by which kidney-tonifying Chinese herbs inhibit osteoclastogenesis: Emphasis on immune cells

Jiao

Wang²,

Wang³

et al. 2023

Front. Pharmacol.

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The immune system plays a crucial role in regulating osteoclast formation and function and has significance for the occurrence and development of immune-mediated bone diseases. Kidney-tonifying Chinese herbs, based on the theory of traditional Chinese medicine (TCM) to unify the kidney and strengthen the bone, have been widely used in the prevention and treatment of bone diseases. The common botanical drugs are tonifying kidney-yang and nourishing kidney-yin herbs, which are divided into two parts: one is the compound prescription of TCM, and the other is the single preparation of TCM and its active ingredients. These botanical drugs regulate osteoclastogenesis directly and indirectly by immune cells, however, we have limited information on the differences between the two botanical drugs in osteoimmunology. In this review, the mechanism by which kidney-tonifying Chinese herbs inhibiting osteoclastogenesis was investigated, emphasizing the immune response. The differences in the mechanism of action between tonifying kidney-yang herbs and nourishing kidney-yin herbs were analysed, and the therapeutic value for immune-mediated bone diseases was evaluated.

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Section: Immunoregulation Mechanisms By Which Tonifying Kidney-yang H...mentioning

confidence: 99%

Mechanisms by which kidney-tonifying Chinese herbs inhibit osteoclastogenesis: Emphasis on immune cells

Jiao

Wang²,

Wang³

et al. 2023

Front. Pharmacol.

View full text Add to dashboard Cite

show abstract

Corrigendum to “The Antiosteoporosis Effects of Yishen Bugu Ye Based on Its Regulation on the Differentiation of Osteoblast and Osteoclast”

Cited by 1 publication

References 1 publication

Mechanisms by which kidney-tonifying Chinese herbs inhibit osteoclastogenesis: Emphasis on immune cells

Mechanisms by which kidney-tonifying Chinese herbs inhibit osteoclastogenesis: Emphasis on immune cells

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