Corrigendum to “Immediate effects of deep brain stimulation of the subthalamic nucleus on nonmotor symptoms in Parkinson's disease” [Parkinsonism Relat Disord (2012) 994–997]

Wolz, Martin; Hauschild, Julia; Koy, Jan; Fauser, Mareike; Klingelhöfer, Lisa; Schackert, Gabriele; Reichmann, Heinz; Storch, Alexander

doi:10.1016/j.parkreldis.2013.09.002

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study found no significant difference in NMSS scores between awake and asleep groups. Previous studies reported improved NMSS scores for patients who underwent STN-DBS, but there was no comparative study in NMSS scores between awake and asleep DBS groups (Nazzaro et al, 2011;Wolz et al, 2012;Dafsari et al, 2016).…”

Section: Non-motor Outcomementioning

confidence: 98%

The efficacy and safety of asleep and awake subthalamic deep brain stimulation for Parkinson’s disease patients: A 1-year follow-up

Chen

Zhang

Jiang

et al. 2023

Front. Aging Neurosci.

View full text Add to dashboard Cite

IntroductionTraditional DBS is usually conducted under local anesthesia (LA) which is intolerable to some patients, DBS under general anesthesia (GA) was opted to extended surgical indication. This study aimed to compare the efficacy and safety of bilateral subthalamic deep brain stimulation (STN-DBS) for Parkinson’s disease (PD) under asleep and awake anesthesia state in 1-year postoperative follow-up.MethodsTwenty-one PD patients were assigned to asleep group and 25 patients to awake group. Patients received bilateral STN-DBS under different anesthesia state. The PD participants were interviewed and assessed preoperatively and at 1-year postoperative follow-up.ResultsAt 1-year follow-up, compared surgical coordinate in two groups, the left-side Y of asleep group showed more posterior than awake group (Y was-2.39 ± 0.23 in asleep group, −1.46 ± 0.22 in awake group, p = 0.007). Compared with preoperative OFF MED state, MDS-UPDRS III scores in OFF MED/OFF STIM state remained unchanged, while in OFF MED/ON STIM state were significantly improved in awake and asleep groups, yet without significant difference. Compared with preoperative ON MED state, MDS-UPDRS III scores in ON MED/OFF STIM, and ON MED/ON STIM state remained unchanged in both groups. In non-motor outcomes, PSQI, HAMD, and HAMA score significantly improved in asleep group compared to awake group at 1-year follow-up (PSQI, HAMD, and HAMA score in 1-year follow-up were 9.81 ± 4.43; 10.00 ± 5.80; 5.71 ± 4.75 in awake group, 6.64 ± 4.14; 5.32 ± 3.78; 3.76 ± 3.87 in asleep group, p = 0.009; 0.008; 0.015, respectively), while there was no significant difference in PDQ-39, NMSS, ESS, PDSS score, and cognitive function. Anesthesia methods was significantly associated with improvement of HAMA and HAMD score (p = 0.029; 0.002, respectively). No difference in LEDD, stimulation parameters and adverse events was observed between two groups.DiscussionAsleep STN-DBS may be considered a good alternative method for PD patients. It is largely consistent with awake STN-DBS in motor symptoms and safety. Yet, it showed higher improvement in terms of mood and sleep compared to awake group at 1-year follow-up.

show abstract

Section: Non-motor Outcomementioning

confidence: 98%

The efficacy and safety of asleep and awake subthalamic deep brain stimulation for Parkinson’s disease patients: A 1-year follow-up

Chen

Zhang

Jiang

et al. 2023

Front. Aging Neurosci.

View full text Add to dashboard Cite

show abstract

The Psychiatric and Neuropsychiatric Symptoms After Subthalamic Stimulation for Parkinson’s Disease

Mosley¹,

Marsh²

2015

JNP

View full text Add to dashboard Cite

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established treatment for the motor symptoms of Parkinson's disease (PD). Nonmotor features of PD, however, may not improve with STN DBS, and a specific constellation of neuropsychiatric symptoms may emerge in the postoperative period. Mania, impulsivity, depression, and apathy may curtail the potential gains from surgery. In this paper, the authors discuss surgical candidacy, postoperative management of neuropsychiatric issues, and clinical dilemmas for the psychiatrist at the DBS center. A paradigm that considers stimulation effects and dopamine replacement therapy to be key drivers of postoperative neuropsychiatric problems is presented.

show abstract

Corrigendum to “Immediate effects of deep brain stimulation of the subthalamic nucleus on nonmotor symptoms in Parkinson's disease” [Parkinsonism Relat Disord (2012) 994–997]

Cited by 2 publications

References 0 publications

The efficacy and safety of asleep and awake subthalamic deep brain stimulation for Parkinson’s disease patients: A 1-year follow-up

The efficacy and safety of asleep and awake subthalamic deep brain stimulation for Parkinson’s disease patients: A 1-year follow-up

The Psychiatric and Neuropsychiatric Symptoms After Subthalamic Stimulation for Parkinson’s Disease

Contact Info

Product

Resources

About