Corrigendum to “Effects of Sevoflurane and Propofol on Organ Blood Flow in Left Ventricular Assist Devices in Pigs”

Morillas-Sendín, Paloma; Delgado-Baeza, Emilio; Delgado-Martos, María Jesús; Barranco, Mónica; Cañizo, Juan F. Del; Ruíz, Manuel; Quintana‐Villamandos, Begoña

doi:10.1155/2016/4152173

Cited by 1 publication

(1 citation statement)

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“…Sample size calculation was based on the hypothesis that TCI propofol provides stability in intraoperative hemodynamic as a single agent. According to previous studies [25–27], the mean decrease in MAP after induction was 23 (SD = 8) and CI was 2.6 (SD = 0.19) in TCI propofol groups, and the mean decrease in MAP after induction was 28 (SD = 5) in the sevoflurane group, and CI was 2.0 (SD = 1.03) in the sevoflurane group. A difference of 20% in CI and MAP between the 2 groups after induction was considered as clinically relevant.…”

Section: Methodsmentioning

confidence: 71%

Comparison of the Effects of Target-Controlled Infusion of Propofol and Sevoflurane as Maintenance of Anesthesia on Hemodynamic Profile in Kidney Transplantation

Aditianingsih

Sukmono

Agung

et al. 2019

Anesthesiology Research and Practice

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Background Target-controlled infusion (TCI) propofol and sevoflurane are common agents for general anesthesia, including for kidney transplantation procedure. This study compared the effect of TCI propofol and sevoflurane on intraoperative hemodynamic profile in kidney transplant patients. Methods A single-blinded prospective study was performed in 46 kidney transplant recipients who were randomized into receiving TCI propofol or sevoflurane as anesthetics maintenance. Hemodynamic parameters such as mean arterial pressure (MAP), cardiac index (CI), stroke volume index (SVI), and systemic vascular resistance index (SVRI) were measured at baseline before induction, postintubation, first surgical incision, every 15 minutes after the first incision, reperfusion, and 15 minutes after reperfusion. Data were analyzed using unpaired t-test, paired t-test, and general linear model. Results Intraoperative MAP, CI, SVI, and SVRI changes were similar in both groups (p = 0.480, 0.216, 0.086, and 0.054). In comparison to the baseline value, TCI propofol and sevoflurane groups showed significant reductions of MAP at postintubation (p=0.010; p < 0.001) and during the first surgical incision (p=0.009; p < 0.001); significant reduction of CI at postintubation (p=0.003; p < 0.001) and during the first surgical incision (p < 0.001; p < 0.001); significant reduction of SVI at postintubation (p=0.013; p=0.008), during the first surgical incision (p=0.008; p=0.003), and 15 minutes after reperfusion (p=0.010; p=0.005); and significant increasing of SVRI during the first surgical incision (p=0.007; p=0.005). The TCI propofol group showed significantly lower SVRI compared to the sevoflurane group postintubation (p=0.029) and during the first surgical incision (p=0.026). Conclusion Intraoperative hemodynamic profile was similar between the TCI propofol and sevoflurane group during kidney transplant surgery. The TCI propofol group had higher CI and SVI but showed significantly lower SVRI as compared to the sevoflurane group. The incidence of postanesthesia agitation, postoperative outcome, and complication were not significantly different between the two groups.

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Section: Methodsmentioning

confidence: 71%