Corrigendum to “Citric acid crosslinked cyclodextrin/hydroxypropylmethylcellulose hydrogel films for hydrophobic drug delivery” [Int. J. Biol. Macromol. 93 (2016) 75–86]

Fabrication of citric acid crosslinked β‐cyclodextrin/hydroxyethylcellulose hydrogel films for controlled delivery of poorly soluble drugs

“…These groups may undergo ionization in buffer leading to the generation of a mild acidic environment within the hydrogel film for some time. This may cause ionization of KTZ molecules to some extent and enhance their release . The βCD‐ g ‐HEC hydrogel films (except H3) significantly retarded the release of KTZ than H0 ( p < 0.05) with H1 showing a minimum release of 49.92 ± 1.66% in 6 h. This may be due to the continuous complexation and decomplexation phenomena exhibited by the active βCD molecules in the hydrogel films .…”

“…The addition of βCD in feed may reduce the formation of HEC–HEC crosslinks due to the dilution effect and facilitate the formation of βCD–HEC and βCD–βCD crosslinks (see Figure ). The βCD‐HEC crosslinks help to graft the βCD molecules on the HEC chains in the hydrogel films whereas the βCD–βCD crosslinking leads to the formation of a water soluble conjugate which gets removed during the washing of the hydrogel films . Besides, there may be formation of HEC–βCD–HEC and HEC–βCD–βCD–HEC type of crosslinks.…”

“…Taking into consideration all these advantages of citric acid, we had prepared βCD grafted hydroxypropylmethylcellulose (βCD‐HPMC) and carboxymethylcellulose (βCD‐CMC) hydrogel films for the controlled release of ketoconazole, using citric acid as a crosslinking agent . Due to low swellability, βCD‐HPMC hydrogel films showed poor drug loading.…”

Kinetics of Drug Release via Nicardipine Hydrochloride‐loaded Carboxymethyl Cellulose/Poly(D,L‐lactic‐co‐glycolic acid) Nanocarriers Using a Contemporary Emulsion Process

“…This synthesis approach assisted in solvation of NCH, which is insoluble in polymeric solution but dissolves in the acid solution. Citric acid is an ingredients in the NCH injection formulation [29] and a cross‐linker of CMC [30,31] . To dissolve NCH in the acidic solution, solid NCH was first dissolved in citric acid in a separate solution, and then, the NCH solution was combined with the CMC solution to obtain citric acid‐crosslinked CMC nanogel particles.…”

Formation and characterization of zinc oxide complexes in composite hydrogel films for potential wound healing applications

“…These characteristics make hydrogels an excellent candidate for various biomedical applications, especially as a component in wound healing materials . Among several polymers of cellulose derivatives, sodium carboxymethylcellulose (NaCMC) and hydroxypropylmethylcellulose (HPMC) have been widely investigated to fabricate hydrogels for wound healing applications . Both polymers exhibit a higher swelling rate in saline solutions and distilled water in comparison to other cellulose ethers .…”