Corrigendum to “Chlorogenic acid attenuates glucotoxicity in H9c2 cells via inhibition of glycation and PKC α upregulation and safeguarding innate antioxidant status” [Biomed. Pharmacother. 100 (2018) 467–477]

R, Preetha Rani M; Nair, Anupama; Mohan, Sreelekshmi; Raghu, Kozhiparambil Gopalan

doi:10.1016/j.biopha.2020.111071

Cited by 1 publication

(1 citation statement)

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“…According to these findings, it can be concluded that the combination therapy (CGA+GEN) could lead to the best outcomes for modulating these Acta Biochimica Iranica 1(3): 145-153 Acta Biochimica Iranica oxidative stress parameters in skeletal muscle compared to single treatments. In agreement with the effects of CGA, in a study conducted by Preetha Rani et al, it has been demonstrated that CGA, through the antioxidant activity, significantly attenuates hyperglycemia in H9c2 cells (54). The result of Huang's study showed that the stimulation of antioxidant scavenging enzymes and the inhibition of lipid peroxidation were linked to protective effects of GEN on oxidative stress followed by recovery of liver damage and liver fibrosis induced by alcohol administration in rats (55).…”

Section: Discussionmentioning

confidence: 53%

Genistein in combination with Chlorogenic acid ameliorates insulin resistance and oxidative stress in skeletal muscle of high-fat diet fed mice

Goodarzi,

Yadollahi,

Tehrani

et al. 2023

ABI

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Objectives: Increasing evidence has demonstrated that oxidative stress plays a significant role in the pathogenesis of muscle insulin resistance. The beneficial impacts of genistein (GEN) and chlorogenic acid (CGA) on insulin resistance have already been revealed. However, their combined effects on skeletal muscle oxidative stress and insulin resistance have not been completely understood. The aim of the present study was to determine the effect of GEN in combination with CGA on skeletal muscle insulin resistance in high-fat diet (HFD) fed C57BL/6 mice. Methods: C57BL/6 male mice were fed an HFD for 15 weeks. The mice were then divided into five groups: standard chow diet (SCD), HFD, HFD + GEN, HFD + CGA, and HFD + GEN + CGA for 10 weeks. Results: The findings indicated that single treatment with GEN or CGA, and with a stronger effect of GEN+CGA combined treatment, decreased body weight gain and improved glucose intolerance. Moreover, following treatment with GEN and CGA alone or in combination with further effect, the level of plasma and muscle triglyceride (TG) were reduced. Furthermore, the combination therapy of GEN and CGA with greater efficacy than the single treatments, could decrease several oxidative stress markers in the skeletal muscle. Treatment with GEN and CGA alone or in combination could increase the expression of NF-E2–related factor 2 (Nrf2), heme oxygenase-1 (HO-1), and NAD(P): Quinone Oxidoreductase 1 (NQO1). Conclusion: The data of this study suggest that the combination of GEN and CGA might ameliorate insulin resistance and reduce oxidative stress in the skeletal muscle of mice fed HFD.

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Section: Discussionmentioning

confidence: 53%