Corrigendum to “Characterization of Zebrafish von Willebrand Factor Reveals Conservation of Domain Structure, Multimerization, and Intracellular Storage”

Role of PmRab7 Regulation in WSSV Infection and Functional Validation of Small Molecule as PmRab7 GTPase Inhibitor

“…In agreement with this, the PmRab7 gene sequence codes for a deduced polypeptide containing five extremely conserved motifs (G boxes) involved in GTP-binding or GTPase activity and an isoprenylation site (last both C), suggesting that PmRab7 is an active GTPase that is able to cycle between GDP-and GTP bound states [22]. In this study we presented 3D model of PmRab7 for Mg 2+ and GTP binding site analysis, the same model was shown by Arunima et al [23] also, but here first time we are reporting the inactive PmRab7 (GDP) to active PmRab7 (GTP) on the basis of various hydrogen bonding G 18-20, T 46 and K 126 were involved in PmRab7 activation. In the present molecular docking study, CID 1067700 was docked with PmRab7 (Target protein PDB Id: 1VG8) using the docking program GLIDE in the presence of Mg 2+ and GTP.…”