“…Thus, to estimate maximum pinch force, we prescribed force in increasing 10N intervals, and interpreted a threshold force, beyond which the algorithm failed to identify muscle coordination patterns that produced greater forces, as an indicator of maximum strength. To predict maximal fingertip or pinch strength, other studies have used forward simulations; however, these simulations occurred in a mechanically static framework [9,10,42,69]. For example, we previously replicated the methods of [9], to simulate lateral pinch with the same thumb model used here in a different computational environment [10,69].…”