Corrigenda: Computational Handbook of Statistics.

Bruning, James L.; Kintz, B. L.

doi:10.2307/2286125

Cited by 120 publications

(137 citation statements)

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“…To ensure that blood gas parameters were unaffected by the muscimol (or saline), a parallel group of animals were subjected to the same drug (n = 3) or saline (n = 3) treatment as before, but as well as measuring blood gases before the injection, they were measured again at the beginning and at the end of a 45-s infusion of saline, replacing the iso tope solution normally used in the experiments. Statistical comparisons of local cerebral blood flow within each cortical area were performed using an exten sion of the analysis of variance based upon the t distri bution to allow multiple comparisons to be made (Bruning and Klintz, 1977). The comparisons of interest, deter mined a priori, were between saline treatment and each of the two time points after muscimol injection.…”

Section: Methodsmentioning

confidence: 99%

The Effects of the GABA Agonist Muscimol upon Blood Flow in Different Vascular Territories of the Rat Cortex

Kelly

Faulkner

Burrow

1989

J Cereb Blood Flow Metab

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Summary: Local cerebral blood flow was measured in five regions of rat cortex immediately following intrave nous administration of the ,),-aminobutyric acid (GABA) agonist muscimol. In contrast to recent observations, no increases in blood flow were found at either of the two time points analysed, and the data revealed that de creases in blood flow previously reported 30 min after muscimol treatment were in evidence as early as 30 s. These results are totally consistent with the conclusion

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Section: Methodsmentioning

confidence: 99%

The Effects of the GABA Agonist Muscimol upon Blood Flow in Different Vascular Territories of the Rat Cortex

Kelly

Faulkner

Burrow

1989

J Cereb Blood Flow Metab

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“…The percentages presented in the tables represent the proportion of the total grooming score (T = 100%) displayed by the rats following a particular treatment. Statistical evaluation of the data was performed by analysis of variance (ANOVA) in combination with a supplemental t-test (Bruning and Kintz, 1977).…”

Section: Methodsmentioning

confidence: 99%

Excessive grooming induced by somatostatin or its analog SMS 201-995

Greidanus

Maigret

Krechting

1987

European Journal of Pharmacology

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Intracerebroventricular (i.c.v.) administration of somatostatin or SMS 201-995 induces excessive grooming behavior in rats. The grooming inducing effect of somatostatin is rather weak, as doses of 300 ng or less did not result in increased total grooming scores. In contrast a dose of 10 ng SMS 201-995 already significantly increased the total grooming scores. However, doses of 100 ng and more did not further increase the total grooming scores reached with a 50 ng dose of this peptide. Systemic administration of SMS 201-995 in doses up to 900 ~tg did not result in excessive grooming behavior. Fhe patterns of excessive grooming induced by i.c.v. SMS 201-995 and somatostatin were characterized by a predominant display of scratching. Since peptide-induced scratching is mainly due to activation of opiate receptor systems it is suggested that opiate receptors are involved in the behavioral response to SMS 201-995 and somatostatin administration. This suggestion is further supported by the suppressive effect of naloxone on excessive grooming induced by these peptides. Haloperidol and neurotensin also suppress the excessive grooming induced by somatostatin but not that induced by SMS 201-995. Finally, tolerance developed to the grooming-inducing effect of SMS 201-995 and somatostatin. In addition there was cross tolerance between somatostatin and SMS 201-995.Somatostatin; SMS 201-995; Grooming behavior

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“…This analytical procedure is ideally suited for determining differences in rate with respect to animals reaching a set criterion (SPSS; Chicago, Il). An additional analysis used a proportion test to compare performance patterns in which animals reach criterion at different rates (Bruning JL, 1997). Food intakes during the 6-hr daily session were recorded to the nearest 0.1 g and converted to Kcals.…”

Section: Statistical Analysesmentioning

confidence: 99%

Impairment of acquisition of cocaine self-administration in rats maintained on a high-fat diet

Wellman

Nation

Davis

2007

Pharmacology Biochemistry and Behavior

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Rationale: Variation in dietary constituents such as carbohydrate are known to alter psychostimulant function in brain. Relatively few studies have examined the reinforcing effects of psychostimulants in subjects maintained on high-fat diets. The present experiment compared the rate of acquisition of an operant response for intravenous (i.v.) cocaine infusions (0.2 mg/kg) in rats fed either a chow-pellet diet or a 35.9% (by weight) high-fat diet for 45 days prior to cocaine selfadministration testing.Results: Rats maintained on a high-fat diet for 45 days exhibited diminished acquisition of cocaine self-administration, and this effect was not a function of dietary-induced obesity. Conclusions:The results suggest that prolonged exposure to a high-fat diet diminishes the efficacy of cocaine reinforcement.

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Corrigenda: Computational Handbook of Statistics.

Cited by 120 publications

References 0 publications

The Effects of the GABA Agonist Muscimol upon Blood Flow in Different Vascular Territories of the Rat Cortex

The Effects of the GABA Agonist Muscimol upon Blood Flow in Different Vascular Territories of the Rat Cortex

Excessive grooming induced by somatostatin or its analog SMS 201-995

Impairment of acquisition of cocaine self-administration in rats maintained on a high-fat diet

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