Correspondence
PUVA therapy of granuloma annulare

Psoralen and ultraviolet A in the treatment of granuloma annulare

“…PUVA is a well‐recognized treatment for many inflammatory skin diseases. While there have been previous reports in the literature to support the use of PUVA in the treatment of GA (2–6), the patient numbers in these studies have been small. These reports showed clearance after 2–4 months of treatment but in two reports patients required maintenance therapy on a weekly (3) or twice monthly (5) basis in order to maintain remission.…”

“…Psoralen and ultraviolet A (PUVA) is a well-established treatment option for many inflammatory dermatoses. There is some evidence to support the use of PUVA in the treatment of GA, with reports of clearance rates of 70% (2) and prolonged remission, albeit in small numbers of patients (2)(3)(4)(5)(6).…”

Light‐ and laser‐based treatments for granuloma annulare: A systematic review

“…Eligibility criteria for this review were established using the population, intervention, comparator, outcomes, and study design (PICOS) mnemonic, a framework used to encapsulate several key components of the review's aim 16 . Studies were included if they met the predetermined PICOS criteria: Population: individuals of any age and sex diagnosed with GA, including any disease severity, treatment history or comorbid conditions Intervention: phototherapy including oral, bath, and cream PUVA; UVB, nbUVB, and excimer laser; UVA1; methyl aminolevulinate (MAL) PDT and 5‐aminolevulinic acid (ALA) PDT; and laser‐ and energy‐based devices (pulsed dye laser (PDL) and fractional erbium 2940nm laser) Comparator: untreated individuals with GA or in the absence of a comparator, open‐label studies where outcomes were assessed in treated individuals with GA Outcomes: clinical response, adverse events, recurrence, lesion count, visual analogue scale, Dermatology Life Quality Index, healing time, physician global assessment, and patient satisfaction Study design: cohort studies, cross‐sectional studies, case‐control studies, and case series. …”

Necrobiosis lipoidica and granuloma annulare: Part 2- Granuloma annulare

“…A variety of systemic therapies have been described including oral corticosteroids, antibiotics, antimalarials, fumaric acid esters, 23 isotretinoin, biologic (anti-TNF) agents, ciclosporin, dapsone, niacinamide, vitamin E, chlorambucil, pentoxifylline, PUVA 24 and narrow-band ultraviolet B phototherapy. 4,6,19 Resolution of GA was reported in a case of a Japanese female with hypertriglyceridaemia with a strict lipid-lowering diet.…”