Correspondence on ‘Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the global burden of disease study 2017’

Chiang, Ping-Hao; Ju, Po-Chung; Chiang, Yun-Chi; Wei, James Cheng‐Chung

doi:10.1136/annrheumdis-2020-219522

Cited by 3 publications

(5 citation statements)

References 6 publications

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“…2 For exact occupations, it is unfortunately impossible to divide patients with musculoskeletal (MSK) disorders into groups according to their occupations since there are no corresponding estimates from the Global Burden of Disease study 2017. 3 4 We agree with your comments on effects of social risk factors and occupational risks between high and low human development index (HDI) countries 1 ; in our study, a stable or increasing trend of age-standardised incidence rate (ASR) for low back pain (LBP) was observed. 2 However, occupational risks attributable to ASR might be more likely to be modified among countries and territories with higher HDI.…”

supporting

confidence: 68%

“…You indicated that Taiwan's HDI in 2019 was 0.911. 1 We are not sure of its comparability with the other data from the Human Development Report. Moreover, we need data in 1990 and 2017.…”

mentioning

confidence: 96%

“…Response to: 'Correspondence on 'Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the Global Burden of Disease study 2017' by Chiang et al We appreciate Chiang et al 1 for their interest and comments on our research article entitled 'Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the global burden of disease study 2017'. 2 For exact occupations, it is unfortunately impossible to divide patients with musculoskeletal (MSK) disorders into groups according to their occupations since there are no corresponding estimates from the Global Burden of Disease study 2017.…”

mentioning

confidence: 99%

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Response to: ‘Correspondence on ‘Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the Global Burden of Disease study 2017’ by Chianget al

2020

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supporting

confidence: 68%

“…You indicated that Taiwan's HDI in 2019 was 0.911. 1 We are not sure of its comparability with the other data from the Human Development Report. Moreover, we need data in 1990 and 2017.…”

mentioning

confidence: 96%

mentioning

confidence: 99%

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Response to: ‘Correspondence on ‘Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the Global Burden of Disease study 2017’ by Chianget al

2020

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“…IVDD not only causes great suffering to the lives and spirits of patients, but it also places a heavy financial burden on those individuals, their families, and the entire nation. [3] Patients with IVDD are currently treated mostly with 2 forms of conservative and surgical ways. Physical therapy and medications can help early-stage IVDD patients with their long-term pain, but they cannot address the underlying causes of the disease or its mechanism of action.…”

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confidence: 99%

Exploring the pharmacological mechanism of Duhuo Jisheng Decoction in treating intervertebral disc degeneration based on network pharmacology

et al. 2023

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Background: The purpose of this study was to examine the mechanism of Duhuo Jisheng Decoction (DHJSD) in the treatment of intervertebral disc degeneration (IVDD). Methods: The active compounds of DHJSD and their corresponding targets were obtained from the TCMSP database. “Intervertebral disc degeneration” was used as a search term in the DisGeNET, GeneCards, Comparative Toxicogenomics Database, and MalaCards database to obtain disease-related targets. Following the discovery of overlapping DHJSD and IVDD targets, enrichment analyses for Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, Reactome, and WikiPathways were performed. Cytoscape 3.9.1 was used to build the “DHJSD-Active Ingredients-Target Genes-IVDD” network and protein-protein interaction network, and CytoHubba was used to screen the pivotal genes. Molecular docking confirmed the binding activity of hub genes and key components. Results: The bioinformatic analysis of DHJSD in the treatment of IVDD revealed 209 potential therapeutic gene targets, including 36 important gene targets and 10 of these crucial gene targets. Enrichment analysis of 36 key therapeutic targets showed that the biological processes involved in the Gene Ontology analysis of DHJSD in treating IVDD were mainly cytokine-mediated signaling pathway, inflammatory response, negative regulation of apoptotic process, and vascular endothelial growth factor production. The Kyoto Encyclopedia of Genes and Genomes signaling pathway is mainly involved in TNF signaling pathway, Th17 cell differentiation, IL-17 signaling pathway, and HIF-1 signaling pathway. The Recactome signaling pathway is mainly involved in cytokine signaling in immune system, cellular responses to stress, immune system, cytokines, and inflammatory response. HIF1A and PPARG regulation of glycolysis are mostly involved in the WikiPathways signaling system. The findings demonstrated that to cure IVDD, DHJSD affects the pathogenic processes of inflammation, extracellular matrix, cellular senescence, autophagy, apoptosis, focal death, and proliferation through the aforementioned targets and signaling pathways. The results of molecular docking demonstrated that the protein can be effectively bound by the DHJSD active component. Further evidence was provided for the molecular mechanism through which DHJSD works to treat IVDD. Conclusion: This study uncovers the multi-component, multi-target, and multi-pathway characteristics of DHJSD for the treatment of IVDD, offering fresh perspectives to further investigate the mechanism of DHJSD for the treatment of IVDD.

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“…The global prevalence of arthritis is ∼0.34% to 0.36% 1–3 . The most common types of arthritis are osteoarthritis (OA), rheumatoid arthritis (RA), psoriatic arthritis (PsA), and gouty arthritis (GA).…”

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confidence: 99%

Microneedling in the relief of pain in arthritis: a brief review

Chen

Mao

et al. 2023

Interdisciplinary Nursing Research

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Pain is the main symptom of arthritis. Microneedling is a new method of transdermal drug delivery that relives the pain in arthritis according to the mechanisms of pain in arthritis. This paper provides a review of the mechanisms of pain in arthritis and the use of different types of microneedles (MNs) in pain relief in arthritis. The mechanism of pain in arthritis is primarily a joint tissue lesion that causes the release of inflammatory factors by pro-inflammatory cells, resulting in pain. MNs can carry various drugs to reduce inflammatory factors, cartilage destruction and thus the symptom of pain. MNs can be classified into five types, which are solid MNs, hollow MNs, coated MNs, dissolving MNs, and swelling MNs. Among them, dissolving MNs and swelling MNs have better prospects for application in long-term management of pain in arthritis due to the biosafety of their materials and its convenience brought by the sustained-release design.

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Correspondence on ‘Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the global burden of disease study 2017’

Abstract: Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

Cited by 3 publications

References 6 publications

Response to: ‘Correspondence on ‘Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the Global Burden of Disease study 2017’ by Chianget al

Response to: ‘Correspondence on ‘Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the Global Burden of Disease study 2017’ by Chianget al

Exploring the pharmacological mechanism of Duhuo Jisheng Decoction in treating intervertebral disc degeneration based on network pharmacology

Microneedling in the relief of pain in arthritis: a brief review

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