Correspondence: An attempt to produce immune complexes in experimental syphilis.

Wicher, Konrad; Wicher, Victoria; Dąbrowski, M

doi:10.1136/sti.50.4.319

Cited by 1 publication

(2 citation statements)

References 6 publications

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“…with only small varia tions <luring treatment. Similar results have been reported by Wicher et al (27) when studying rabbits infected with Treponema pallidum. One patient (no.…”

Section: Discussionsupporting

confidence: 90%

“…The examinations for proteinuria were not carried out systematically, but the frequency of proteinuria has earlier been de terminated to be 7 % (9). Wicher et al (27) who infected 34 rabbits with Treponema pallidum found normal kidney function and normal histopathology of the kidneys 5 to 6 months after infection. Conse quently circulating immune complexes can be pres ent in the blood without affecting the kidneys.…”

Section: Discussionmentioning

confidence: 97%

See 1 more Smart Citation

Circulating immune complexes in syphilis

Sølling¹,

Sølling²,

Ku³

et al. 1978

Acta Derm Venereol

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13 patients with syphilis were investigated regarding the presence of circulating immune complexes by the methods of C 1q-binding-activity and anticomplementarity. Elevated C1q-binding-activity was demonstrated in 6 of 7 patients with secondary syphilis, a significantly greater incidence than among patients with primary syphilis and neurosyphilis. Anticomplementarity was demonstrated in five of seven patients with secondary syphilis and in two patients with neurosyphilis. Anticomplementarity was found in only one of four patients with primary syphilis. The presence of immune complexes may be of importance in the aetiology of some of the lesions of secondary and perhaps tertiary syphilis.

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“…with only small varia tions <luring treatment. Similar results have been reported by Wicher et al (27) when studying rabbits infected with Treponema pallidum. One patient (no.…”

Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 97%