Correlationship between c-erB2 protein expression and clinical outcome in gastric cancer.

Evaluation of the Epidermal Growth Factor Receptor (EGFR) and c-erbB-2 in Superspreading-type and Penetrating-type Gastric Carcinoma.

“…Our results suggested that the autocrine mechanism of the growth factors was correlated with the degree of gastric wall invasion, too. Yonemura et al [9] reported that the positive staining of c-erbB-2 was correlated with positive serosal invasion, lymph node metastasis, larger tumors (greater than 6 cm), and with prognosis. Tokunaga et al [8] reported that the expression of c-erbB-2 was correlated with the histological type, lymph node metastasis, serosal invasion of the tumor, and with prognosis.…”